CAJ | 학술논문

目的：观察海参冻干粉治疗更年期综合征肾阳虚证的临床疗效，并观察其对患者性激素水平的影响。方法选择30例更年期综合征肾阳虚证患者，观察并分析患者海参冻干粉治疗前后Kupperman症状评分和临床疗效，并分别测定患者治疗前后雌二醇（E2）、促卵泡生成激素（FSH）和促黄体生成激素（LH），比较其治疗前后的变化情况。结果海参冻干粉治疗后与治疗前相比，患者临床症状明显改善，临床总有效率为90％，Kupperman评分差异有统计学意义（P＜0．01）；海参冻干粉治疗后患者血清FSH、LH水平较治疗前下降，血清E2水平较治疗前升高，差异有统计学意义（P＜0．05）。结论海参冻干粉对更年期综合征肾阳虚证具有较好的治疗作用，对患者性激素水平有调节作用。
목적：관찰해삼동간분치료경년기종합정신양허증적림상료효，병관찰기대환자성격소수평적영향。방법선택30례경년기종합정신양허증환자，관찰병분석환자해삼동간분치료전후Kupperman증상평분화림상료효，병분별측정환자치료전후자이순（E2）、촉란포생성격소（FSH）화촉황체생성격소（LH），비교기치료전후적변화정황。결과해삼동간분치료후여치료전상비，환자림상증상명현개선，림상총유효솔위90％，Kupperman평분차이유통계학의의（P＜0．01）；해삼동간분치료후환자혈청FSH、LH수평교치료전하강，혈청E2수평교치료전승고，차이유통계학의의（P＜0．05）。결론해삼동간분대경년기종합정신양허증구유교호적치료작용，대환자성격소수평유조절작용。
Objective To observe the effect of freeze-dried sea cucumber powder in the treatment of patients with kidney-yang deficiency of perimenopause syndrome ,and to observe its effect on the levels of gonadal hormone . Methods 30 patients with kidney-yang deficiency of perimenopause syndrome were selected ,the changes of the Kup-perman score,the clinical effect and the levels of serum E2,FSH and LH before and after treatment were observed. Results After treatment,the clinical symptoms were significantly improved and the total effective rate was 90%.The improvement of Kupperman scores had significant difference (P<0.01).The serum level of E2 was increased signifi-cantly after treatment (P<0.05),while the serum levels of FSH and LH were decreased significantly (P<0.05). Conclusion Freeze-dried sea cucumber powder in the treatment of patients with kidney-yang deficiency of perimeno-pause syndrome has preferable clinical effects and can modify gonadal hormone levels .