CAJ | 학술논문

随着人们对于肿瘤性疾病的发生、发展、转移机制的进一步探索，循环肿瘤细胞（CTCs）逐渐进入人们视野，其应用价值日益体现，可用于肿瘤性疾病的早期诊断及治疗效果的监测，尤其是对于早期肿瘤的诊断具有独特优势。其富集技术及检测方法也在发生着日新月异的变化。近年来，微流控分析芯片技术运用于 CTCs 的富集及检测，具有高丰度、高富集度、高活性及不需要对样本进行预处理等优点使得人们聚焦于此技术，本文对微流控分析芯片在 CTCs 检测中的运用做简要综述。
수착인문대우종류성질병적발생、발전、전이궤제적진일보탐색，순배종류세포（CTCs）축점진입인문시야，기응용개치일익체현，가용우종류성질병적조기진단급치료효과적감측，우기시대우조기종류적진단구유독특우세。기부집기술급검측방법야재발생착일신월이적변화。근년래，미류공분석심편기술운용우 CTCs 적부집급검측，구유고봉도、고부집도、고활성급불수요대양본진행예처리등우점사득인문취초우차기술，본문대미류공분석심편재 CTCs 검측중적운용주간요종술。
Circulating tumor cells play an important role with the further recognition of the mechanism of the occurrence development and metastasis of the tumor disease ,and it can be used for the early tumor diagnosis and therapeutic effect monitoring ,especially for the early stage of tumor disease diagnosis .The technology of enrich and detection of the CTCs develops rapidly .So many enrichment and detection technology appear so fast .Recently ,microfluidic device has been focused because of the advantages of its high accuracy ,high enrichment ,high activity ,no need to pre-modified .In this paper ,a brief overview of the use of microfluidic device in the detection of the circulating tumor cells was given .