CAJ | 학술논문

目的：研究高选择性?受体阻滞剂比索洛尔（康可）对慢性肺源性心脏病心力衰竭患者的病死率、住院率及心功能改善方面的疗效。方法102例慢性肺心病心衰患者随机分成两组：对照组50例，给予常规治疗；治疗组52例，给予常规治疗加比索洛尔2.5～10mg/d,随访一年。结果随访一年时，治疗组和对照组相比，在预定的终点死亡率明显降低，2例对15例，与对照组相比治疗组心衰恶化患者住院率下降，患者心功能（nYHa）分级、心律失常改善更明显，不良反应轻微。结论比索洛尔治疗慢性肺心病患者，可降低死亡率、住院率，改善心功能状态而具有良好的耐受性。
목적：연구고선택성?수체조체제비색락이（강가）대만성폐원성심장병심력쇠갈환자적병사솔、주원솔급심공능개선방면적료효。방법102례만성폐심병심쇠환자수궤분성량조：대조조50례，급여상규치료；치료조52례，급여상규치료가비색락이2.5～10mg/d,수방일년。결과수방일년시，치료조화대조조상비，재예정적종점사망솔명현강저，2례대15례，여대조조상비치료조심쇠악화환자주원솔하강，환자심공능（nYHa）분급、심률실상개선경명현，불량반응경미。결론비색락이치료만성폐심병환자，가강저사망솔、주원솔，개선심공능상태이구유량호적내수성。
Objective to study the high selectivity of ?-blocker bisoprolol (Kang Ke) on the curative effect of chronic pulmonary heart disease mortality in patients with heart failure, improve the rate of hospitalization rate and cardiac function. Methods 102 cases of chronicpulmonary heart disease were randomly divided into two groups:50 cases in the control group, treated with conventional treatment;52 cases in the treatment group were given conventional treatment, Gabi snoyl 2.5~10mg/d, one year of follow-up. One year follow-up,compared to the treatment group and the control group,signiifcantly reduce mortality in the end a predetermined,2 cases of 15 cases, compared with the control group the treatment group decreased the rate of hospitalized patients with heart failure, cardiac function (NYHA),cardiac arrhythmia classiifcation improved obviously,adverse reaction of light micro. Conclusion bisoprolol in treatment of patients with chronic pulmonary heart disease, which can reduce the mortality, hospitalization rate, improve heart function and has good tolerance.