CAJ | 학술논문

目的：探讨欧米诺汗印法对糖尿病足溃疡（DFU）发生风险的预测价值。方法以振动觉阈值（VPT）作为评估DFU发生风险的标准将725例2型糖尿病（T2DM）患者分为DFU高危组和非高危组。利用受试者工作特征（ROC）曲线比较欧米诺汗印法与10 g尼龙单丝（10 g SWMF）检查对DFU发生风险的预测价值。结果725例T2DM患者中DFU高危组占6.1%，该组患者的年龄、DM病程、欧米诺颜色完全变化（CCC）时间及10 g SWMF异常率均高于非高危组（P<0.01）。ROC曲线提示欧米诺CCC时间对DFU发生风险的预测作用优于10 g SWMF，前者ROC曲线下面积约0.8，最佳切点为22.25 min。结论欧米诺汗印法能有效预测DFU发生风险，在预防DFU中具有重要应用价值。
목적：탐토구미낙한인법대당뇨병족궤양（DFU）발생풍험적예측개치。방법이진동각역치（VPT）작위평고DFU발생풍험적표준장725례2형당뇨병（T2DM）환자분위DFU고위조화비고위조。이용수시자공작특정（ROC）곡선비교구미낙한인법여10 g니룡단사（10 g SWMF）검사대DFU발생풍험적예측개치。결과725례T2DM환자중DFU고위조점6.1%，해조환자적년령、DM병정、구미낙안색완전변화（CCC）시간급10 g SWMF이상솔균고우비고위조（P<0.01）。ROC곡선제시구미낙CCC시간대DFU발생풍험적예측작용우우10 g SWMF，전자ROC곡선하면적약0.8，최가절점위22.25 min。결론구미낙한인법능유효예측DFU발생풍험，재예방DFU중구유중요응용개치。
Objective To assess the predictive value of Neuropad test on occurrence of diabetic foot ulceration (DFU) among type 2 diabetic patients. Methods We divided 725 cases of type 2 diabetic patients into the high-risk and the non-high-risk groups of DFU based on the results of vibration perception thresholds(VPT) examination, which was widely used as a criteria for predicting DFU. Receiver operating characteristic (ROC) analysis was used to compare the effectiveness of Neuropad with 10 g Semmes-Weinstein monofilament (10 g SWMF) testing in predicting the risk of DFU. Results Among 725 patients of type 2 diabetes, 6.1% were at a high risk of DFU. Compared to non-high-risk group, patients in high-risk group had older age, longer diabetes duration, higher values of complete colour change time (CCC time) of Neuropad and higher abnormal rate of 10 g SWMF (P<0.01). CCC time of Neuropad was shown to be better in predicting the risk of DFU than 10 g SWMF, and the area under the ROC curve was about 0.8, and the best cut-off value was 22.25 min. Conclusion Neuropad is an effective means for predicting of the risk of DFU, and can be used to prevent diabetic foot ulceration.