CAJ | 학술논문

目的：探讨娱乐性体力活动与中老年子宫肌瘤（UL）危险性之间的关系。方法采用以医院为基础的病例对照研究方法，选择35~62岁UL患者353例（UL组），同时选择同期入住相同医院按年龄进行频数匹配的353例非UL患者为对照组。采用调查表对研究对象进行调查，内容包括：人口学特征、身体测量值、生活方式以及疾病既往史等。还采用国际体力活动调查表（IPAQ）对研究对象的体力活动情况进行调查。应用多因素Logistic回归分析估计娱乐性体力活动与UL关联的比值比（OR）及其相应的95%可信区间（CI）。结果 UL组产次≥2的比例明显低于对照组，UL组的高血压和糖尿病患者均高于对照组。调整多种潜在性混杂因素后，与MET为最低四分位数的对照相比较，MET为第二、三个四分位数的病例发生UL的危险性均降低。能量消耗为第二、三个四分位数的病例发生UL的危险性显著地低于能量消耗为最低四分位数的对照。结论进行丰富的娱乐性体力活动，可能有助于预防UL。
목적：탐토오악성체력활동여중노년자궁기류（UL）위험성지간적관계。방법채용이의원위기출적병례대조연구방법，선택35~62세UL환자353례（UL조），동시선택동기입주상동의원안년령진행빈수필배적353례비UL환자위대조조。채용조사표대연구대상진행조사，내용포괄：인구학특정、신체측량치、생활방식이급질병기왕사등。환채용국제체력활동조사표（IPAQ）대연구대상적체력활동정황진행조사。응용다인소Logistic회귀분석고계오악성체력활동여UL관련적비치비（OR）급기상응적95%가신구간（CI）。결과 UL조산차≥2적비례명현저우대조조，UL조적고혈압화당뇨병환자균고우대조조。조정다충잠재성혼잡인소후，여MET위최저사분위수적대조상비교，MET위제이、삼개사분위수적병례발생UL적위험성균강저。능량소모위제이、삼개사분위수적병례발생UL적위험성현저지저우능량소모위최저사분위수적대조。결론진행봉부적오악성체력활동，가능유조우예방UL。
Objective To investigate the association between recreational physical activity and uterine leiomyoma (UL) in middle and elderly women. Methods A hospital-based case-control study was conducted. Cases (n=353) were patients with UL 35~62 years old, and controls (n=353) were patients who had been admitted to the same hospital for dis-eases not related with UL. All subjects were interviewed using an interviewer-administrated questionnaire that included in-formation on personal characteristics, anthropometric characteristics, lifestyle habits and medical history. Then physical ac-tivities were investigated using international physical activity questionnaire (IPAQ). The odds ratios (OR) and 95%confi-dence intervals (CI) of UL for recreational physical activity were estimated with multiple logistic regression models. Results Personal characteristics (age and marital status) were not statistically significant different between the two groups. However, the percentage of controls with number of live births ≥2 was significantly lower than cases. Simultaneously, hypertension and diabetes patients in case groups were higher than controls. After adjusting for multiple potential confounders, compared to the controls in lowest quartile, cases in the second and third quartile of MET had lower risks for UL. Compared to the lowest quartile, cases in the second and third quartile of energy expended had lower risks. Conclusion Various recre-ational physical activity can be protective to UL.