CAJ | 학술논문

目的：初步研究柳州市2～6岁学龄前儿童血红蛋白（Hbg）水平，制订该地区学龄前儿童Hbg的参考范围，为临床儿童疾病的诊断提供参考值和相关依据。方法收集2012年1月至2013年6月在该院儿童保健中心进行健康体检的学龄前儿童12416例，采集静脉血，用全自动血液细胞分析仪测定Hbg，按性别、年龄分组，并进行统计学分析。结果12416例学龄前儿童平均Hbg水平为（20.99±9.07）g/L。＞5～6岁组学龄前儿童平均Hbg水平[（124.43±9.53）g/L]较其他年龄组高，差异有统计学意义（P<0.05）；＞4～5岁组学龄前儿童平均Hbg水平[（121.74±9.40）g/L]较大于2～3岁组高[（120.57±8.98）g/L]，差异有统计学意义（P=0.016），各年龄组不同性别学龄前儿童平均Hbg水平比较，差异均无统计学意义（P＞0.05）。结论柳州市学龄前儿童平均Hbg水平存在年龄差异，各实验室及不同测定方法应根据不同地域、不同年龄建立合适的Hbg参考范围。
목적：초보연구류주시2～6세학령전인동혈홍단백（Hbg）수평，제정해지구학령전인동Hbg적삼고범위，위림상인동질병적진단제공삼고치화상관의거。방법수집2012년1월지2013년6월재해원인동보건중심진행건강체검적학령전인동12416례，채집정맥혈，용전자동혈액세포분석의측정Hbg，안성별、년령분조，병진행통계학분석。결과12416례학령전인동평균Hbg수평위（20.99±9.07）g/L。＞5～6세조학령전인동평균Hbg수평[（124.43±9.53）g/L]교기타년령조고，차이유통계학의의（P<0.05）；＞4～5세조학령전인동평균Hbg수평[（121.74±9.40）g/L]교대우2～3세조고[（120.57±8.98）g/L]，차이유통계학의의（P=0.016），각년령조불동성별학령전인동평균Hbg수평비교，차이균무통계학의의（P＞0.05）。결론류주시학령전인동평균Hbg수평존재년령차이，각실험실급불동측정방법응근거불동지역、불동년령건립합괄적Hbg삼고범위。
Objective To study the hemoglobin (Hbg) level of 2-6-year-old preschoolers in Liuzhou city initially and for-mulate a reference range of Hbg for the preschoolers in the area ,so as to provide reference value and relevant basis for diagnosis of children disease in clinic. Methods Venous blood samples were collected from 12 ,416 healthy preschoolers during January 2012-June 2013 in the Child Health Center of the hospital ,and the Hbg was measured by blood analyzer. The statistical analysis was conducted in gender and age groups. Results The average Hbg level of 12 416 preschoolers was (120.99±9.07)g/L. The group with children>5-6 years old had higher average levels of Hbg (124.43±9.53)g/L than the other age groups with statistically significant difference(P<0.05);the average Hbg level in the group with children >4-5 years old[(121.74±9.40)g/L] was higher than that in the group with children>2-3 years old[(120.57±8.98)g/L],and the difference was statistically significant(P=0.016). The comparison of the average Hbg level among the groups with different genders and ages demonstrated no statistically significant difference (P>0.05). Conclusion The Hbg level of the preschoolers in Liuzhou city varies by age. It should establish an appro-priate reference range with different regions and ages with different determination methods in the laboratory.