中国实用医药
中國實用醫藥
중국실용의약
CHINA PRACTICAL MEDICAL
2014年
9期
1-3
,共3页
庞俊%李浩%潘莲花%韦淑珍%黄绍标
龐俊%李浩%潘蓮花%韋淑珍%黃紹標
방준%리호%반연화%위숙진%황소표
艾滋病病毒(HIV)%艾滋病(AIDS)%宫颈癌%癌前病变%影响因素
艾滋病病毒(HIV)%艾滋病(AIDS)%宮頸癌%癌前病變%影響因素
애자병병독(HIV)%애자병(AIDS)%궁경암%암전병변%영향인소
Human immunodeficiency virus(HIV)%Acquired immune deficiency syndrome(AIDS)%Cervical cancer%Precancerous lesions%Influence factors
目的探讨艾滋病病毒(HIV)感染者和艾滋病(AIDS)患者合并宫颈癌与癌前病变的相关影响因素。方法以在本院诊治的40例HIV/AIDS(HIV抗体阳性)合并宫颈癌与癌前病变患者为观察组,等距抽样选择同期在本院诊治的40例HIV抗体阴性宫颈癌与癌前病变患者为对照组,对其相关危险行为、宫颈癌与癌前病变的程度进行横断面调查。结果观察组中HIV感染者19例(47.50%), AIDS患者21例(52.50%)；两组多性伴、性病史、配偶/固定性伴有多性伴、配偶/固定性伴HIV抗体阳性差异具有高度统计学意义(45.00%比10.00%、37.50%比7.50%、82.50%比27.50%、72.50%比2.50%, P均<0.01)；两组宫颈病变不同程度中CINⅢ与宫颈癌的发生率差异具有高度统计学意义(57.50%比15.00%与27.50%比2.5%, P均<0.01), CINⅡ的发生率与孕次≥3次比较差异无统计学意义(15.00%比32.50%,65.00%比50.00%)。结论 HIV/AIDS患者合并宫颈癌与癌前病变的影响因素与多性伴、性病史、配偶/固定性伴有多性伴、配偶/固定性伴HIV抗体阳性密切相关；HIV抗体阳性者CIN Ⅲ与宫颈癌的发生率显著高于HIV抗体阴性者。
目的探討艾滋病病毒(HIV)感染者和艾滋病(AIDS)患者閤併宮頸癌與癌前病變的相關影響因素。方法以在本院診治的40例HIV/AIDS(HIV抗體暘性)閤併宮頸癌與癌前病變患者為觀察組,等距抽樣選擇同期在本院診治的40例HIV抗體陰性宮頸癌與癌前病變患者為對照組,對其相關危險行為、宮頸癌與癌前病變的程度進行橫斷麵調查。結果觀察組中HIV感染者19例(47.50%), AIDS患者21例(52.50%)；兩組多性伴、性病史、配偶/固定性伴有多性伴、配偶/固定性伴HIV抗體暘性差異具有高度統計學意義(45.00%比10.00%、37.50%比7.50%、82.50%比27.50%、72.50%比2.50%, P均<0.01)；兩組宮頸病變不同程度中CINⅢ與宮頸癌的髮生率差異具有高度統計學意義(57.50%比15.00%與27.50%比2.5%, P均<0.01), CINⅡ的髮生率與孕次≥3次比較差異無統計學意義(15.00%比32.50%,65.00%比50.00%)。結論 HIV/AIDS患者閤併宮頸癌與癌前病變的影響因素與多性伴、性病史、配偶/固定性伴有多性伴、配偶/固定性伴HIV抗體暘性密切相關；HIV抗體暘性者CIN Ⅲ與宮頸癌的髮生率顯著高于HIV抗體陰性者。
목적탐토애자병병독(HIV)감염자화애자병(AIDS)환자합병궁경암여암전병변적상관영향인소。방법이재본원진치적40례HIV/AIDS(HIV항체양성)합병궁경암여암전병변환자위관찰조,등거추양선택동기재본원진치적40례HIV항체음성궁경암여암전병변환자위대조조,대기상관위험행위、궁경암여암전병변적정도진행횡단면조사。결과관찰조중HIV감염자19례(47.50%), AIDS환자21례(52.50%)；량조다성반、성병사、배우/고정성반유다성반、배우/고정성반HIV항체양성차이구유고도통계학의의(45.00%비10.00%、37.50%비7.50%、82.50%비27.50%、72.50%비2.50%, P균<0.01)；량조궁경병변불동정도중CINⅢ여궁경암적발생솔차이구유고도통계학의의(57.50%비15.00%여27.50%비2.5%, P균<0.01), CINⅡ적발생솔여잉차≥3차비교차이무통계학의의(15.00%비32.50%,65.00%비50.00%)。결론 HIV/AIDS환자합병궁경암여암전병변적영향인소여다성반、성병사、배우/고정성반유다성반、배우/고정성반HIV항체양성밀절상관；HIV항체양성자CIN Ⅲ여궁경암적발생솔현저고우HIV항체음성자。
Objective To explore the related influence factors of cervical cancer/precancerous lesions on patients with HIV/AIDS. Methods Took 40 cases of inpatients with HIV/AIDS(HIV-positive) and with cervical cancer /precancerous lesions as observation group, chose 40 cases of HIV-negative inpatients with cervical cancer/precancerous lesions for the period by interval sampling. Investigated them on cross section by related risky behaviors and the levels of cancer/precancerous lesions. Results For the observation group, there were 19 HIV-infected cases(47.50%) and 21 others AIDS patients(52.50%). Between the two group there was highly significant difference among factors of multiple sexual partner, venereal history, multiple sexual partner for spouse/regular sex partner, HIV-positive spouse/regular sex partner(45.00%VS 10.00%、37.50%VS 7.50%、82.50%VS 27.50%、72.50%VS 2.50%,P<0.01). On different levels of cervical lesions, there was highly significant difference in incidence of cervical cancer for patients with CIN III while with CIN II and gravidity more than 3 times, there’s no significant difference(15.00%VS 32.50%,65.00%VS 50.00%). Conclusion The influence factors of closely related with multiple sexual partner, venereal history, multiple sexual partner for spouse/regular sex partner, HIV-positive spouse/regular sex partner. The incidence of cervical cancer for patients with CIN III is higher than those with HIV-negative.
