实用口腔医学杂志
實用口腔醫學雜誌
실용구강의학잡지
JOURNAL OF PRACTICAL STOMATOLOGY
2014年
2期
223-226
,共4页
薛毅%吴仲寅%赵进%李凤和
薛毅%吳仲寅%趙進%李鳳和
설의%오중인%조진%리봉화
慢性牙周炎%龈沟液(GCF)%Ⅰ型胶原羧基端交联肽(CTX)%酶联免疫吸附实验(ELISA)
慢性牙週炎%齦溝液(GCF)%Ⅰ型膠原羧基耑交聯肽(CTX)%酶聯免疫吸附實驗(ELISA)
만성아주염%간구액(GCF)%Ⅰ형효원최기단교련태(CTX)%매련면역흡부실험(ELISA)
Chronic periodontitis%Gingival crevicular fluid(GCF)%C-terminal telopeptides oftype I collagen (CTX)%Enzyme-linked immunosorbent assay(ELISA)
目的:探讨龈沟液中 I 型胶原羧基端交联肽(C-terminal telopeptides of type I collagen,CTX)水平与常用牙周炎临床检测指标的相关性。方法:选择就诊牙周病患者60例的77颗牙齿,采用酶联免疫吸附法测定其龈沟液中 CTX 水平,并对临床牙周检查的常用几个指标菌斑指数(PL)、牙龈指数(GI)、牙周袋探诊深度(PD)、附着丧失(AL)进行记录,用 SPSS 11.0软件秩和检验分析各指标与龈沟液中 CTX 的相关性。结果:PL、GI、PD、AL 与龈沟液中 CTX 浓度的 Sperman 秩相关系数分别为0.386(P <0.01),0.366(P <0.05),0.382(P <0.05)和0.314(P <0.05)。结论:龈沟液中 CTX 浓度与 PL、GI、PD、AL 成正相关。
目的:探討齦溝液中 I 型膠原羧基耑交聯肽(C-terminal telopeptides of type I collagen,CTX)水平與常用牙週炎臨床檢測指標的相關性。方法:選擇就診牙週病患者60例的77顆牙齒,採用酶聯免疫吸附法測定其齦溝液中 CTX 水平,併對臨床牙週檢查的常用幾箇指標菌斑指數(PL)、牙齦指數(GI)、牙週袋探診深度(PD)、附著喪失(AL)進行記錄,用 SPSS 11.0軟件秩和檢驗分析各指標與齦溝液中 CTX 的相關性。結果:PL、GI、PD、AL 與齦溝液中 CTX 濃度的 Sperman 秩相關繫數分彆為0.386(P <0.01),0.366(P <0.05),0.382(P <0.05)和0.314(P <0.05)。結論:齦溝液中 CTX 濃度與 PL、GI、PD、AL 成正相關。
목적:탐토간구액중 I 형효원최기단교련태(C-terminal telopeptides of type I collagen,CTX)수평여상용아주염림상검측지표적상관성。방법:선택취진아주병환자60례적77과아치,채용매련면역흡부법측정기간구액중 CTX 수평,병대림상아주검사적상용궤개지표균반지수(PL)、아간지수(GI)、아주대탐진심도(PD)、부착상실(AL)진행기록,용 SPSS 11.0연건질화검험분석각지표여간구액중 CTX 적상관성。결과:PL、GI、PD、AL 여간구액중 CTX 농도적 Sperman 질상관계수분별위0.386(P <0.01),0.366(P <0.05),0.382(P <0.05)화0.314(P <0.05)。결론:간구액중 CTX 농도여 PL、GI、PD、AL 성정상관。
Objective:To detect the correlativity between clinical periodental indexes and C-terminal telopeptides of type I collagen (CTX)concentration in gingival crevicular fluid(GCF).Methods:77 teeth with periodontitis in 60 patients from the international Bethune peace hospital were included.The concentration of CTX in GCF was detected by enzyme-linked immunosorbent assay.The plague indexe(PL),gingival indexe(GI),probing depth(PD)and attachment loss (AL)level were recorded at clinic.The correla-tion of CTX concentration and clinic indexes was analysed by Kruskal-Wallis test using SPSS 1 1 .0 software.Results:The Spearman correlation coefficient of PL,GI,PD and AL with CTX was 0.386(P <0.01 ),0.366(P <0.05),0.382(P <0.05)and 0.31 4(P <0.05)respectively.Conclusion:PL,GI,PD and AL are positively correlated with the concentration of CTX in GCF(P <0.05).