CAJ | 학술논문

目的：探讨非溶栓脑梗死出血性转化（hemorrhagic transformation，HT）的危险因素。方法运用SPSS13.0软件对同期58例非溶栓脑梗死继发HT的病例和58例单纯脑梗死病例，对包括高血压病史、梗死面积、高胆固醇血症及心房颤动史等20项因素进行单因素分析和回顾性分析。结果两组患者Logistic回归分析显示，有统计学意义的有4项因素，根据OR值的大小依次排列为：脑梗死面积（OR=8.386，95%CI：3.237~28.326，P=0.003）、尿蛋白阳性（OR=5.622，95%CI：3.231~21.359，P=0.011）、心房颤动史（OR=4.923，95%CI：1.062~18.967，P=0.038）、血糖（OR=4.286，95%CI：1.027~16.481，P=0.042）。结论梗死面积、尿蛋白阳性、心房颤动史及高血糖是发生HT的危险因素。
목적：탐토비용전뇌경사출혈성전화（hemorrhagic transformation，HT）적위험인소。방법운용SPSS13.0연건대동기58례비용전뇌경사계발HT적병례화58례단순뇌경사병례，대포괄고혈압병사、경사면적、고담고순혈증급심방전동사등20항인소진행단인소분석화회고성분석。결과량조환자Logistic회귀분석현시，유통계학의의적유4항인소，근거OR치적대소의차배렬위：뇌경사면적（OR=8.386，95%CI：3.237~28.326，P=0.003）、뇨단백양성（OR=5.622，95%CI：3.231~21.359，P=0.011）、심방전동사（OR=4.923，95%CI：1.062~18.967，P=0.038）、혈당（OR=4.286，95%CI：1.027~16.481，P=0.042）。결론경사면적、뇨단백양성、심방전동사급고혈당시발생HT적위험인소。
Objective To investigate the non-hemorrhagic transformation of cerebral infarction thrombolysis(hemorrhagic transformation,HT) risk factors. Methods Using SPSS13. 0 software over the same period 58 cases of cerebral infarction secondary to non-thrombolysis cases and 58 cases of HT in simple cases,including a history of hypertension cerebral infarction, infarc t size,hypercholesterolemia,and history of atrial fibrillation and other 20 univariate analysis and retrospectively analyzed. Results Logistic regression analysis showed that two groups of patients were statistically significant in four factors,according to the size of the OR values in order of priority as follows:infarct size (OR=8.386,95%CI:3.237~28.326,P=0.003),urinary protein positive (OR=5.622,95%CI:3.231~21.359,P=0.011),history of atrial fibrillation (OR=4.923,95%CI:1.062~18.967, P=0.038),blood glucose (OR=4.286,95%CI:1.027~16.481,P=0.042). Conclusions Infarct size,urinary protein,atrial fibrillation and history of high blood sugar are risk factors of HT.