中国肝脏病杂志(电子版)
中國肝髒病雜誌(電子版)
중국간장병잡지(전자판)
CHINESE JOURNAL OF LIVER DISEASES(ELECTRONIC VERSION)
2014年
2期
47-49
,共3页
肝硬化%胃肠道%奥曲肽%垂体激素类,后叶%治疗学
肝硬化%胃腸道%奧麯肽%垂體激素類,後葉%治療學
간경화%위장도%오곡태%수체격소류,후협%치료학
Liver cirrhosis%Gastrointestinal tract%Octreotide%Pituitary hormones,posterior%Trerapeutics
目的:探索肝硬化上消化道出血(UGH)的有效治疗药物。方法选择79例肝硬化UGH患者,临床采用随机分组的方式分为观察组(42例)和对照组(37例)。两组患者在输血、补液、抑酸剂、预防感染、抗肝性脑病、维持水电解质与酸碱平衡等治疗基础上,观察组应用奥曲肽0.1 mg静脉推注后,给予50μg/h持续静脉输注;对照组给予垂体后叶素20 U静脉推注后,给予0.5 U/min持续静脉输注。结果观察组和对照组患者显效率为64.3%和37.8%(P=0.0086),总有效率为95.2%和78.4%(P=0.0228)。结论奥曲肽是治疗肝硬化UGH的安全、有效的药物。
目的:探索肝硬化上消化道齣血(UGH)的有效治療藥物。方法選擇79例肝硬化UGH患者,臨床採用隨機分組的方式分為觀察組(42例)和對照組(37例)。兩組患者在輸血、補液、抑痠劑、預防感染、抗肝性腦病、維持水電解質與痠堿平衡等治療基礎上,觀察組應用奧麯肽0.1 mg靜脈推註後,給予50μg/h持續靜脈輸註;對照組給予垂體後葉素20 U靜脈推註後,給予0.5 U/min持續靜脈輸註。結果觀察組和對照組患者顯效率為64.3%和37.8%(P=0.0086),總有效率為95.2%和78.4%(P=0.0228)。結論奧麯肽是治療肝硬化UGH的安全、有效的藥物。
목적:탐색간경화상소화도출혈(UGH)적유효치료약물。방법선택79례간경화UGH환자,림상채용수궤분조적방식분위관찰조(42례)화대조조(37례)。량조환자재수혈、보액、억산제、예방감염、항간성뇌병、유지수전해질여산감평형등치료기출상,관찰조응용오곡태0.1 mg정맥추주후,급여50μg/h지속정맥수주;대조조급여수체후협소20 U정맥추주후,급여0.5 U/min지속정맥수주。결과관찰조화대조조환자현효솔위64.3%화37.8%(P=0.0086),총유효솔위95.2%화78.4%(P=0.0228)。결론오곡태시치료간경화UGH적안전、유효적약물。
Objective To observe the effect of octreotide on upper gastrointestinal hemorrhage (UGH) in patients with liver cirrhosis. Methods Total of 79 cases of UGH patients were randomly divided into treatment group and control group. The two groups were defined on the basis of the internal medical treatment, 37 patients in the control group, were treated with pituitrin, 42 patients in the treatment group, were treated with octreotide. Results The difference of efifciency in two groups is signiifcant 37.8%and 64.3%(P=0.0086). Total effective rates were 78.4%and 95.2%(P=0.0228), respectively. Conclusions Octreotide was safe and effective for the treatment of UGH in patients with liver cirrhosis.