CAJ | 학술논문

目的：评估高压氧早期干预新生儿缺血缺氧性脑病的作用。方法：收集2009年1月至2012年12月高州市人民医院收治的381例缺血缺氧性脑病新生儿，分为对照组(199例)和治疗组(182例)。采用运动发育量表PDMS-2评估治疗效果。结果：治疗组治疗后的GMQ、TMQ评分优于对照组( P<0.05)，后遗症发生率低于对照组( P<0.05)。结论：对于新生儿缺血缺氧性脑病，高压氧早期干预能起到明显的治疗效果，但必须明确高压氧治疗的适应证，以减小可能带来的并发症。
목적：평고고압양조기간예신생인결혈결양성뇌병적작용。방법：수집2009년1월지2012년12월고주시인민의원수치적381례결혈결양성뇌병신생인，분위대조조(199례)화치료조(182례)。채용운동발육량표PDMS-2평고치료효과。결과：치료조치료후적GMQ、TMQ평분우우대조조( P<0.05)，후유증발생솔저우대조조( P<0.05)。결론：대우신생인결혈결양성뇌병，고압양조기간예능기도명현적치료효과，단필수명학고압양치료적괄응증，이감소가능대래적병발증。
Objective:To explore the effects of hyperbaric oxygen ( HBO) for neonatal hypoxic-ischemic encephalopathy ( HIE ) . Methods: Neonates diagnosed with HIE were recruited between January 2009 and October 2012 form Gaozhou People’s Hospital. Neonates were randomly assigned to control group(n=199)and treatment group ( n=182) . Peabody Development Motor Scale-2 was used to evaluate the therapeutic effect before and after HBO treatment. Results:After treatment with HBO,the GMQ (84.2±19.6 vs. 79.7±18.2) and TMQ scores (85.1±21.2 vs 80.6±19.2) in treatment group were markedly higher and the sequalae were significantly less than in control group ( all P<0.05) . Conclusion:Early intervention with HBO is effective for neonatal HIE. The indications of HBO,however,should be well managed to reduce the possible risks of sequalae.