CAJ | 학술논문

目的：探讨监测脑钠肽( BNP )对判断老年感染性休克患者预后的临床意义。方法：回顾性分析78例于2007年6月至2013年10月入住的老年感染性休克患者的临床资料，根据其入科6及24 h BNP水平，分为A组(BNP<100 pg/mL)、B组(100 pg/mL≤BNP<500 pg/mL)和C组(BNP≥500 pg/mL)。比较各组24 h内APACHE II评分、6、24 h血乳酸值，ICU住院时间及患者入ICU后28 d内死亡率。结果：A组和B组APACHE II评分、血乳酸及ICU住院时间，28 d内死亡率比较，差异无统计学意义(P>0.05)，与A组、B组比较，C组上述指标均显著升高( P<0.05)。结论：BNP水平对老年感染性休克患者预后的判断有一定意义，BNP水平≥500 pg/mL可能是患者病情加重及死亡率增高的一个重要判断指标。
목적：탐토감측뇌납태( BNP )대판단노년감염성휴극환자예후적림상의의。방법：회고성분석78례우2007년6월지2013년10월입주적노년감염성휴극환자적림상자료，근거기입과6급24 h BNP수평，분위A조(BNP<100 pg/mL)、B조(100 pg/mL≤BNP<500 pg/mL)화C조(BNP≥500 pg/mL)。비교각조24 h내APACHE II평분、6、24 h혈유산치，ICU주원시간급환자입ICU후28 d내사망솔。결과：A조화B조APACHE II평분、혈유산급ICU주원시간，28 d내사망솔비교，차이무통계학의의(P>0.05)，여A조、B조비교，C조상술지표균현저승고( P<0.05)。결론：BNP수평대노년감염성휴극환자예후적판단유일정의의，BNP수평≥500 pg/mL가능시환자병정가중급사망솔증고적일개중요판단지표。
Objective:To investigate the predictability of brain natriuretic peptide ( BNP ) on the prognosis in elderly patients with septic shock. Methods:Seventy-eight elderly patients with septic shock recruited between June 2007 and October 2013 in the Intensive Care Unit, Panyu Hexian Memorial Hospital, were retrospectively analyzed. Patients were,according to their BNP levels at 6 and 24 h after admission,allocated to group A ( BNP<100 pg/mL), group B (100 pg/mL≤BNP<500 pg/mL)and group C (BNP ≥500 pg/mL).The 24-hour APACHE II score, blood lactic acid at 6 and 24 h,length of stay in the intensive care unit and in-hospital mortality within 28 days were compared. Results:There were no significant differences in the APACHE II score,blood lactate,the length of stay in ICU and mortality within 28 days between group A and group B ( all P>0.05) . Compared with groups A and B,all indices were significantly heightened in group C ( all P<0.05) . Conclusion:The level of BNP has considerable predictability on the prognosis of elderly patients with septic shock. BNP being 500 pg/mL or greater may be an important index of exacerbations and higher mortality.