CAJ | 학술논문

目的：探讨Luminal A型与Luminal B型乳腺癌临床病理与超声特征的差异。方法：回顾性分析本院乳腺中心经病理及免疫组化证实97例Luminal A型和54例Luminal B型乳腺癌患者资料，对比分析其临床病理特征与超声学表现。结果：Luminal A型和Luminal B型临床病理特征在组织学分级( P＝0?007)及淋巴结转移率(P＝0.027)，超声学表现在边界(P＝0.039)、微钙化(P＝0.016)及血流分级(P＝0?011)差异有统计学意义。与Luminal A型比较，Luminal B型乳腺癌具有组织学分化低、淋巴结转移率较高、超声学边界不清，微钙化明显、血供丰富等特征。结论：Luminal A型与Luminal B型在临床病理和超声学特征存在一定的差异，对预后的评估及治疗方案的制订有一定的指导作用。
목적：탐토Luminal A형여Luminal B형유선암림상병리여초성특정적차이。방법：회고성분석본원유선중심경병리급면역조화증실97례Luminal A형화54례Luminal B형유선암환자자료，대비분석기림상병리특정여초성학표현。결과：Luminal A형화Luminal B형림상병리특정재조직학분급( P＝0?007)급림파결전이솔(P＝0.027)，초성학표현재변계(P＝0.039)、미개화(P＝0.016)급혈류분급(P＝0?011)차이유통계학의의。여Luminal A형비교，Luminal B형유선암구유조직학분화저、림파결전이솔교고、초성학변계불청，미개화명현、혈공봉부등특정。결론：Luminal A형여Luminal B형재림상병리화초성학특정존재일정적차이，대예후적평고급치료방안적제정유일정적지도작용。
Objective:To compare the clinicopathologic and ultrasonographic characteristics of patients with Luminal A and Luminal B breast carcinoma. Methods: Clinicopathologic and ultrasonographic features of 97 patients with Luminal A and 54 patients with Luminal B breast carcinoma confirmed by pathology and immunohistochemical assay were analyzed retrospectively. Results:Luminal B breast carcinoma was associated with higher cancer grading ( P= 0. 007 ), more pronounced lymph node metastasis ( P= 0. 027 ), unclear boundaries (P=0.039), microcalcification (P=0.016) and higher blood supply (P=0.011) compared with Luminal B breast carcinoma. Conclusion: Luminal A and Luminal B breast carcinomas differ considerably in terms of clinicopathologic and ultrasonographic features and has a role in guiding prognostic evaluation and establishing therapeutic protocols.