中华实验和临床感染病杂志（电子版）
中華實驗和臨床感染病雜誌（電子版）
중화실험화림상감염병잡지（전자판）
CHINESE JOURNAL OF EXPERIMENTAL AND CLINICAL INFECTIOUS DISEASES(ELECTRONIC VERSION)
2014年
3期
418-420
,共3页
陈芳%郝玉清%颜小平%余梅
陳芳%郝玉清%顏小平%餘梅
진방%학옥청%안소평%여매
尿路感染%尿培养%耐药性%抗菌药物
尿路感染%尿培養%耐藥性%抗菌藥物
뇨로감염%뇨배양%내약성%항균약물
Urinary tract infection%Urine culture%Drug resistance%Antibiotics
目的：探讨分析尿路感染患者中段尿培养的结果及耐药性，便于指导临床用药。方法收集本院2012年1月至2013年1月收治的496例尿路感染者，进行了中段尿培养及药敏试验。结果入组496例尿路感染者细菌菌谱中革兰阴性菌（G-）为322株，构成比为64.92%，主要为大肠埃希菌152株（30.65%）；革兰阳性菌（G+）为169株，构成比为34.07%，主要为粪肠球菌48株（9.68%）和屎肠球菌41株（8.27%）；其中真菌感染为5株，构成比为1.01%。选取全部菌种中5类主要菌种进行药敏分析：大肠埃希菌、粪肠球菌、屎肠球菌、凝固酶阴性的葡萄球菌和铜绿假单胞菌，其中G+菌耐药率较高，其中屎肠球菌对于氨苄西林、头孢噻肟、环丙沙星、庆大霉素等抗菌药物的耐药率为100%；凝固酶阴性的葡萄球菌对氨苄西林、头孢噻肟、环丙沙星的耐药率均为100%，对庆大霉素的耐药率为68.57%。结论尿路感染者以革兰阴性菌感染为主，但革兰阳性菌对常规抗菌药物耐药率较高，便于指导临床应用抗菌药物。
目的：探討分析尿路感染患者中段尿培養的結果及耐藥性，便于指導臨床用藥。方法收集本院2012年1月至2013年1月收治的496例尿路感染者，進行瞭中段尿培養及藥敏試驗。結果入組496例尿路感染者細菌菌譜中革蘭陰性菌（G-）為322株，構成比為64.92%，主要為大腸埃希菌152株（30.65%）；革蘭暘性菌（G+）為169株，構成比為34.07%，主要為糞腸毬菌48株（9.68%）和屎腸毬菌41株（8.27%）；其中真菌感染為5株，構成比為1.01%。選取全部菌種中5類主要菌種進行藥敏分析：大腸埃希菌、糞腸毬菌、屎腸毬菌、凝固酶陰性的葡萄毬菌和銅綠假單胞菌，其中G+菌耐藥率較高，其中屎腸毬菌對于氨芐西林、頭孢噻肟、環丙沙星、慶大黴素等抗菌藥物的耐藥率為100%；凝固酶陰性的葡萄毬菌對氨芐西林、頭孢噻肟、環丙沙星的耐藥率均為100%，對慶大黴素的耐藥率為68.57%。結論尿路感染者以革蘭陰性菌感染為主，但革蘭暘性菌對常規抗菌藥物耐藥率較高，便于指導臨床應用抗菌藥物。
목적：탐토분석뇨로감염환자중단뇨배양적결과급내약성，편우지도림상용약。방법수집본원2012년1월지2013년1월수치적496례뇨로감염자，진행료중단뇨배양급약민시험。결과입조496례뇨로감염자세균균보중혁란음성균（G-）위322주，구성비위64.92%，주요위대장애희균152주（30.65%）；혁란양성균（G+）위169주，구성비위34.07%，주요위분장구균48주（9.68%）화시장구균41주（8.27%）；기중진균감염위5주，구성비위1.01%。선취전부균충중5류주요균충진행약민분석：대장애희균、분장구균、시장구균、응고매음성적포도구균화동록가단포균，기중G+균내약솔교고，기중시장구균대우안변서림、두포새우、배병사성、경대매소등항균약물적내약솔위100%；응고매음성적포도구균대안변서림、두포새우、배병사성적내약솔균위100%，대경대매소적내약솔위68.57%。결론뇨로감염자이혁란음성균감염위주，단혁란양성균대상규항균약물내약솔교고，편우지도림상응용항균약물。
Objective To investigate the urine culture results and antibiotic resistance in patients with urinary tract infection, and to guide the application of the clinical medicine.Methods From January 2012 to January 2013, total of 496 cases with urinary tract infection accepted urine culture and sensitivity test.Result Among the 496 cases with urinary tract infection, Gram-negative bacteria (G-) were 322 strains, the constituent ratio was 64.92%, mainly wasE. coli (152 strains, 30.65%); Gram-positive bacteria (G+) were 169 strains (34.07%), the mainly wasEnterococcus faecalis(48 strains, 9.68%) andEnterococcus feces (41 strains, 8.27%). The fungal infection were 5 strains (1.01%).Escherichia coli,Enterococcus faecalis,Enterococcus feces, coagulase-negativeStaphylococci andPseudomonas aeruginosa were selected to sensitivity analysis, the result showed that the G+ had higher resistance rates. TheEnterococcus had a 100%resistance rate to ampicillin, cefotaxime, ciprolfoxacin and gentamicin. The coagulase-negativeStaphylococci had a resistance rate of 100% to ampicillin, cefotaxime, ciprolfoxacin, and it had a resistance rate of 68.57%to gentamicin.Conclusions Urinary tract infection is mainly Gram-negative bacterial infections, but Gram-positive bacteria resistant to conventional antibiotics, with a higher rate, easy to guide the clinical use of antibiotics.
