CAJ | 학술논문

腹膜透析是终末期肾脏病患者的重要替代治疗方式，尽管其短期技术存活率较好，但长期治疗后导致的超滤衰竭，仍然是退出治疗的主要原因。葡萄糖透析液所致的腹膜功能下降与其血管增生和腹膜纤维化密切相关，但是糖尿病、尿毒症毒素、药物、腹膜炎、残余肾功能等诸多因素也影响着腹膜的属性。现就相关的影响因素及其可能的干预方法进行综述。
복막투석시종말기신장병환자적중요체대치료방식，진관기단기기술존활솔교호，단장기치료후도치적초려쇠갈，잉연시퇴출치료적주요원인。포도당투석액소치적복막공능하강여기혈관증생화복막섬유화밀절상관，단시당뇨병、뇨독증독소、약물、복막염、잔여신공능등제다인소야영향착복막적속성。현취상관적영향인소급기가능적간예방법진행종술。
Peritoneal dialysis is an important replacement therapy for end-stage renal disease. Although the short-term technical survival of peritoneal dialysis is good,but ultrafiltration failure after long-term peritoneal dialysis is still the main cause for withdrawal of peritoneal dialysis treatment.The decline in peritoneal function can be attributed to its blood vessel proliferation and peritoneal fibrosis caused by glucose dialysate.However,the peritoneal function may also be affected by many other factors including diabetes, uremic toxins,drugs,peritonitis,and residual renal function.This review has been made regarding the related influencing factors and the possible intervention methods.