CAJ | 학술논문

烯醇化酶是生物体中广泛存在的一种重要的糖酵解酶类，近来发现其还具有激活纤溶酶原的功能，参与寄生虫在宿主体内侵染和转移过程，并能下调宿主免疫功能，协助寄生虫逃避宿主的免疫攻击。本文总结当前对寄生虫烯醇化酶的研究进展，旨在探究其用于寄生虫病诊断、药物研发及疫苗靶标的可能性。
희순화매시생물체중엄범존재적일충중요적당효해매류，근래발현기환구유격활섬용매원적공능，삼여기생충재숙주체내침염화전이과정，병능하조숙주면역공능，협조기생충도피숙주적면역공격。본문총결당전대기생충희순화매적연구진전，지재탐구기용우기생충병진단、약물연발급역묘파표적가능성。
Enolase is one kind of important glycolytic enzymes which widely exists in most organisms. A number of recent studies confirm that this enzyme has the functions of activating the plasminogen involving in the processes of infection and mi-gration of parasites reducing the immune function of the host as well as preventing parasites from the immune attack of the host. This paper reviews the current research advances in the parasite enolase and explores its potential for diagnosis drug develop-ment and vaccine target of parasitic diseases.