CAJ | 학술논문

为了制备具有可控复杂形状和特定化学性质的聚合物微结构，提出了一种飞秒激光直写生物凝胶模板原位合成纳米粒子的方法。首先，采用飞秒激光直写技术加工带有COOH基团的复杂三维结构的生物凝胶模板，用氢氧化钠处理使COOH基团离子化为COO-基团；然后，用金属盐溶液处理，使金属离子与COO-基团螯合，形成纳米粒子结晶核。通过多次循环盐溶液处理步骤，控制模板中纳米粒子的粒径与含量。实验结果表明：所制备的生物凝胶模板具有亚100 nm分辨率和10μm量级尺寸，纳米粒子含量高达9％。该法简单高效，具有很好的应用前景。
위료제비구유가공복잡형상화특정화학성질적취합물미결구，제출료일충비초격광직사생물응효모판원위합성납미입자적방법。수선，채용비초격광직사기술가공대유COOH기단적복잡삼유결구적생물응효모판，용경양화납처리사COOH기단리자화위COO-기단；연후，용금속염용액처리，사금속리자여COO-기단오합，형성납미입자결정핵。통과다차순배염용액처리보취，공제모판중납미입자적립경여함량。실험결과표명：소제비적생물응효모판구유아100 nm분변솔화10μm량급척촌，납미입자함량고체9％。해법간단고효，구유흔호적응용전경。
In order to fabricate polymer microstructures with controllable complex shapes and specific chemical properties , we develop a new method using femtosecond laser direct writing biological gel template to synthesis nanoparticles in-situ.First, we use femtosecond laser direct writing complex three-dimensional (3D) bio gel template with COOH groups , followed by treatment with NaOH solution to change COOH groups into COO -. Then, we put the template in metal salt solution , and make the metal particles chelate with the COO -groups to grow into nanoparticles .Through different cycles of this step , the sizes and content of the nanoparticles in the template can be controlled .The experimental results show that the bio gel templates fabricated by this method have sub 100 nm resolution and 10 μm order size , and the content of the nanoparticles reaches up as high as 9%.This method is simple and efficient , which has a good application prospect .