CAJ | 학술논문

申嗪霉素是中国自主研发的一种新型微生物源农药，具有高效、安全、广谱等特点，其主要成分是甜瓜根际促生菌M18产生的次级代谢产物吩嗪-1-羧酸。文章重点就申嗪霉素产生菌M18的分离及其代谢产物的鉴定、申嗪霉素生物合成及调控机理最新研究进展、申嗪霉素高产工程菌株的构建和产业化、以及申嗪霉素大田防病试验结果及推广应用情况等进行详细综述，并对其抗菌作用机理进行探讨，旨在为申嗪霉素的生物合成机理研究、遗传和代谢改造以及推广应用提供参考。
신진매소시중국자주연발적일충신형미생물원농약，구유고효、안전、엄보등특점，기주요성분시첨과근제촉생균M18산생적차급대사산물분진-1-최산。문장중점취신진매소산생균M18적분리급기대사산물적감정、신진매소생물합성급조공궤리최신연구진전、신진매소고산공정균주적구건화산업화、이급신진매소대전방병시험결과급추엄응용정황등진행상세종술，병대기항균작용궤리진행탐토，지재위신진매소적생물합성궤리연구、유전화대사개조이급추엄응용제공삼고。
Shenqinmycin is a newly developed biopesticide containing the secondary metabolite phenazine-1-carboxylic acid ( PCA ) produced by Pseudomonas sp. M18. The discovery and characterization of Pseudomonas sp. M18 as well as the identification of metabolites were firstly introduced;The progress on Shenqinmycin biosynthetic mechanism and regulatory network was then summarized; The construction of high-yield engineered strain and industrialization of Shenqinmycin were further introduced;Finally, the application of Shenqinmycin in plant disease control and possible antifungal mechanisms of shenqinmycin were discussed.