CAJ | 학술논문

目的：研究多孔磷酸钙骨组织工程支架的表面微纳米化改性。方法通过双氧水发泡法制备多孔磷酸钙骨组织工程支架,利用水热法对材料进行微纳米化表面改性。通过扫描电镜观察材料的显微结构,通过 X 射线衍射仪分析测试材料改性层相成分。结果材料改性处理后,孔隙率为(63±8)%,大孔孔径为(310±30)μm。材料表面及内孔壁生成羟基磷灰石微纳米晶粒或晶须,晶须长20~40μm,直径为100~300 nm。结论多孔磷酸钙陶瓷材料的内外表面经水热法处理微纳米化表面改性后,材料性能得到提升。
목적：연구다공린산개골조직공정지가적표면미납미화개성。방법통과쌍양수발포법제비다공린산개골조직공정지가,이용수열법대재료진행미납미화표면개성。통과소묘전경관찰재료적현미결구,통과 X 사선연사의분석측시재료개성층상성분。결과재료개성처리후,공극솔위(63±8)%,대공공경위(310±30)μm。재료표면급내공벽생성간기린회석미납미정립혹정수,정수장20~40μm,직경위100~300 nm。결론다공린산개도자재료적내외표면경수열법처리미납미화표면개성후,재료성능득도제승。
Objective To research the surface micro/ nano-modification of porous calcium phosphate bone tissue engineering scaffolds. Methods Porous calcium phosphate bone tissue engineering scaffolds were prepared by the H2 O2 foaming method. Then the hydrothermal method was applied for the surface micro/ nano-modification. The scanning electron microscopy (SEM) was used for microstructure observations, and the X-ray diffraction (XRD) was used to analyze the phase composition of the modified layer. Results After the surface modification, scaffolds with a total porosity of (63±8)% , and a pore size of (310±30) μm were ob-tained. The modified surface layers were hydroxyapatite nanocrystals or whiskers, the length of whisker ranged 20 ~ 40 μm, and the diameter was in range of 100 ~ 300 nm. Conclusion The inner and outer surfaces of porous calcium phosphate scaffolds formed a micro/ nano-modification layer by hydrothermal treatment. The performance of the material was improved.