实用临床医学
實用臨床醫學
실용림상의학
Practical Clinical Medicine
2014年
6期
76-78,80
,共4页
外阴阴道假丝酵母菌病,复发性%双唑泰栓%转移因子胶囊%疗效
外陰陰道假絲酵母菌病,複髮性%雙唑泰栓%轉移因子膠囊%療效
외음음도가사효모균병,복발성%쌍서태전%전이인자효낭%료효
recurrence vulvovaginal candidiasis%metronidazole clotrimazole and chlorhexidine acetate%transfer factor capsules%efficacy
目的：探讨双唑泰栓联合转移因子治疗复发性外阴阴道假丝酵母菌病（RVVC）的疗效及安全性。方法将240例RVVC患者按随机数字表法分为治疗组（予双唑泰栓+转移因子胶囊治疗）和对照组（予双唑泰栓治疗），7 d为一疗程，共两疗程，随访3个月。观察2组的临床疗效、不良反应及复发率。结果治疗组总有效率为92.7%，明显高于对照组的81.0%（P<0.05）。治疗组Sobel 评分、复发率均低于对照组（P<0.01）。2组不良反应轻微且差异无统计学意义（P>0.05）。结论双唑泰栓联合转移因子治疗RVVC安全有效，能明显降低复发率。
目的：探討雙唑泰栓聯閤轉移因子治療複髮性外陰陰道假絲酵母菌病（RVVC）的療效及安全性。方法將240例RVVC患者按隨機數字錶法分為治療組（予雙唑泰栓+轉移因子膠囊治療）和對照組（予雙唑泰栓治療），7 d為一療程，共兩療程，隨訪3箇月。觀察2組的臨床療效、不良反應及複髮率。結果治療組總有效率為92.7%，明顯高于對照組的81.0%（P<0.05）。治療組Sobel 評分、複髮率均低于對照組（P<0.01）。2組不良反應輕微且差異無統計學意義（P>0.05）。結論雙唑泰栓聯閤轉移因子治療RVVC安全有效，能明顯降低複髮率。
목적：탐토쌍서태전연합전이인자치료복발성외음음도가사효모균병（RVVC）적료효급안전성。방법장240례RVVC환자안수궤수자표법분위치료조（여쌍서태전+전이인자효낭치료）화대조조（여쌍서태전치료），7 d위일료정，공량료정，수방3개월。관찰2조적림상료효、불량반응급복발솔。결과치료조총유효솔위92.7%，명현고우대조조적81.0%（P<0.05）。치료조Sobel 평분、복발솔균저우대조조（P<0.01）。2조불량반응경미차차이무통계학의의（P>0.05）。결론쌍서태전연합전이인자치료RVVC안전유효，능명현강저복발솔。
Objective To investigate the efficacy and safety of metronidazole clotrimazole and chlorhexidine acetate(MCCA)suppositories combined with transfer factor(TFC)capsules in the treatment of recurrent volvovaginal candidias (RVVC). Methods A total of 240 RVVC patients were randomly treated with MCCA suppositories alone (control group)or in combination with TFC capsules (treatment group) for two weeks. All patients were followed up for 3 months. Clinical efficacy, adverse events and recurrence rate were compared between the two groups. Results Compared with control group, TFC capsules significantly increased the total effective rate (92.7%vs 81.0%,P<0.05)and obviously decreased Sobel score and recurrence rate(P<0.01).Adverse reactions were mild in both groups and the differences were not significant between the two groups(P>0.05). Conclusion MCCA combined with TFC is a safe and effective treatment and can reduce the recurrence rate in RVVC.
