CAJ | 학술논문

目的：探讨低蛋白饮食联合α-酮酸对延缓老年慢性肾功能衰竭（CRF）患者的病情进展、改善营养状况方面的作用。方法：150例老年CRF患者随机分为A、B、C组（各50例），A组予以常规蛋白饮食，B组予以低蛋白饮食，C组予以低蛋白饮食联合复方α-酮酸片，随访1年，监测患者的营养状况指标。结果：与B组患者相比，A、C组患者的营养状况指标升高；C组患者的肾小球滤过率下降速度明显低于A、B组患者。结论：低蛋白饮食联合α-酮酸治疗，可有效延缓老年慢性肾功能衰竭的进展，明显改善患者的营养状况，防止可能出现的营养不良。
목적：탐토저단백음식연합α-동산대연완노년만성신공능쇠갈（CRF）환자적병정진전、개선영양상황방면적작용。방법：150례노년CRF환자수궤분위A、B、C조（각50례），A조여이상규단백음식，B조여이저단백음식，C조여이저단백음식연합복방α-동산편，수방1년，감측환자적영양상황지표。결과：여B조환자상비，A、C조환자적영양상황지표승고；C조환자적신소구려과솔하강속도명현저우A、B조환자。결론：저단백음식연합α-동산치료，가유효연완노년만성신공능쇠갈적진전，명현개선환자적영양상황，방지가능출현적영양불량。
OBJECTIVE:To investigate the effects of α-keto acid plus low-protein diet on delaying the disease progression and improve the nutritional status in elderly patients with chronic renal failure(CRF). METHODS:150 CRF cases were randomized to three groups(group A,B,and C)of 50 each. Group A received routine protein diet,group B received low-protein diet and group C received low-protein diet plus α-keto acid. The patients were followed-up for one year and their nutrition status were monitored. RESULTS:Compared with group B,the nutritional indicators in group A and group C were significantly increased. The reduction speed of glomerular filtration rate in group C was significantly lower than in group A or group B. CONCLUSIONS:The combina-tion of α-keto acid and low-protein diet can effectively delay progression of chronic renal failure while significantly improve the nu-tritional status in elderly patients with CRF.