CAJ | 학술논문

嗜铬细胞瘤起源于肾上腺髓质或其他部位的嗜铬组织，瘤体持续或间断释放儿茶酚胺，引起血压升高、多脏器损害和代谢紊乱，其病情凶险，临床表现变化多端。该文报道1例以心肌梗死、肺炎为首要临床表现，同时并发有脑梗死、肾功能损害以及糖、脂肪、电解质紊乱的嗜铬细胞瘤患者，经血、尿儿茶酚胺及代谢物测定和影像学检查明确诊断，及时给予了抗感染、扩容、改善循环和控制血压等治疗，并于3个月后行手术治疗，随访2年，患者情况稳定。临床上对于高血压合并心肌梗死或脑梗塞患者，要警惕嗜铬细胞瘤的可能，早期诊断和治疗对于患者预后有重要意义。
기락세포류기원우신상선수질혹기타부위적기락조직，류체지속혹간단석방인다분알，인기혈압승고、다장기손해화대사문란，기병정흉험，림상표현변화다단。해문보도1례이심기경사、폐염위수요림상표현，동시병발유뇌경사、신공능손해이급당、지방、전해질문란적기락세포류환자，경혈、뇨인다분알급대사물측정화영상학검사명학진단，급시급여료항감염、확용、개선순배화공제혈압등치료，병우3개월후행수술치료，수방2년，환자정황은정。림상상대우고혈압합병심기경사혹뇌경새환자，요경척기락세포류적가능，조기진단화치료대우환자예후유중요의의。
Pheochromocytoma originates from adrenal medulla or chromaffin tissues of other organs.The tumors persistently or intermittently release catecholamine,leading to elevated blood pressure,damages to multiple organs and metabolic disorders. Pheochromocytoma is characterized with acute and varying clinical manifestations. In this report,the patient,who was diagnosed with pheochromocytoma,presented with myocar-dial infarction and pneumonia as the primary clinical manifestations,complicated with cerebral infarction,renal functional damages,blood glucose,lipid and electrolyte disorders. Determination of urine catecholamine and metabolites and imaging examination confirmed the diagnosis. Anti-infective therapy,volume increment,im-proving circulation and controlling blood pressure were timely delivered. Surgery was conducted at three months subsequently and the patient was followed up for two years. The patient had stable physical conditions. Patients with hypertension complicated with myocardial or cerebral infarction have potential risks of pheochromocytoma.Early diagnosis and treatment play a pivotal role in prognosis of pheochromocytoma.