CAJ | 학술논문

目的：探讨脊髓灰质炎灭活疫苗（IPV）和减毒活疫苗（OPV）不同联合接种方式的临床效果。方法本研究为队列研究，将2009~2013年内收集的在管辖区域具备进行计划免疫4个部门的2400例新生儿进行随机分组，其中一组进行1剂IPV和2剂OPV序贯（I-O-O）（A组），另一组2剂IPV和1剂OPV序贯（I-I-O）（B组），并观察两组新生儿进行接种后的反应。结果这两种方式对于新生儿计划免疫无明显的差异。结论这两种方式对于新生儿进行脊髓灰质炎的计划免疫无不良反应。
목적：탐토척수회질염멸활역묘（IPV）화감독활역묘（OPV）불동연합접충방식적림상효과。방법본연구위대렬연구，장2009~2013년내수집적재관할구역구비진행계화면역4개부문적2400례신생인진행수궤분조，기중일조진행1제IPV화2제OPV서관（I-O-O）（A조），령일조2제IPV화1제OPV서관（I-I-O）（B조），병관찰량조신생인진행접충후적반응。결과저량충방식대우신생인계화면역무명현적차이。결론저량충방식대우신생인진행척수회질염적계화면역무불량반응。
Objective To explore the effect of inactivated poliovirus vaccine (IPV) combined with oral poliovirus vac-cine (OPV). Methods This study was cohort study. Collected 2 400 cases of newborn of four planned immunization depart-ments in our jurisdictions from 2009 to 2013, divided into two groups randomly, 1 dose IPV plus 2 doses OPV(I-O-O,group A), 2 doses IPV plus 1 dose OPV (I-I-O, group B) and observed vaccinated reactions of two groups. Results The two methods had no significant differences in immunization program for newborns. Conclusion The two approaches for newborns po-liovirus immunization with no adverse reaction.