CAJ | 학술논문

目的：分析传染性单核细胞增多综合征病原学构成及临床特点。方法对某院2006年1月-2013年9月住院确诊为传染性单核细胞增多综合征的87例患儿进行病原学检测，并对其临床特点进行总结。结果传染性单核细胞增多综合征居前5位的病原体是肺炎支原体（MP，20例）、巨细胞病毒（CMV，13例）、单纯疱疹病毒（HSV，11例）、衣原体（CP，11例）和细小病毒 B19（Hpv-B19，9例）。各种病原学所致的临床表现大体相同，但各临床症状发生率有所不同。MP 感染以发热及肝、脾、淋巴结大为主，且大部分合并呼吸道并发症（包括喉炎、支气管炎和肺炎等）；CMV 感染也以发热、肝脾大为主，但以肝大更明显；风疹病毒感染其他症状明显，但未出现皮疹。结论传染性单核细胞增多综合征病原学多样，以 MP 感染最常见，其次为 CMV。临床诊断应尽量查明病因，为合理抗感染治疗或去除病因治疗提供理论依据。
목적：분석전염성단핵세포증다종합정병원학구성급림상특점。방법대모원2006년1월-2013년9월주원학진위전염성단핵세포증다종합정적87례환인진행병원학검측，병대기림상특점진행총결。결과전염성단핵세포증다종합정거전5위적병원체시폐염지원체（MP，20례）、거세포병독（CMV，13례）、단순포진병독（HSV，11례）、의원체（CP，11례）화세소병독 B19（Hpv-B19，9례）。각충병원학소치적림상표현대체상동，단각림상증상발생솔유소불동。MP 감염이발열급간、비、림파결대위주，차대부분합병호흡도병발증（포괄후염、지기관염화폐염등）；CMV 감염야이발열、간비대위주，단이간대경명현；풍진병독감염기타증상명현，단미출현피진。결론전염성단핵세포증다종합정병원학다양，이 MP 감염최상견，기차위 CMV。림상진단응진량사명병인，위합리항감염치료혹거제병인치료제공이론의거。
Objective To analyze the etiology and clinical characteristics of infectious mononucleosis-like syndrome (IMLS).Methods Eighty-seven children with IMLS in a hospital from January 2006 to September 2013 were per-formed pathogenic detection,then clinical features were summarized and analyzed.Results The top 5 pathogens in IMLS were Mycoplasma pneumoniae (MP,n=20 ),cytomegalovirus (CMV,n=13),simplex herpes virus(HSV, n=11),Chlamydia (CP,n=11),and parvovirus B19 (Hpv B19,n=9 ),clinical manifestations of all kinds of dis-eases were similar,but the occurrence rates were slightly different.MP infection were mainly fever,hepatospleno-megaly,and lymphadenopathy,and most were associated with respiratory complications(including laryngitis,bron-chitis,and pneumonia),CMV infection were also showed fever and hepatosplenomegaly,but the latter was more ob-vious;rubella patients didn’t appear skin rash,but the other symptoms were obvious.Conclusion Etiologies of in-fectious mononucleosis-like syndrome are varied,MP infection is most common,the next is CMV.Pathogens should be ascertained to provide theoretical basis of treatment.