CAJ | 학술논문

【目的】探讨老年糖尿病（DM ）合并代谢综合征（MS）患者动脉僵硬度的变化及影响因素。【方法】选取来本院疗养的246例老年DM患者，以有无合并MS分为MS组（ n＝120）和无MS组（ n＝126），另选取62例健康老年人作为对照组。对所有患者进行脉搏波传导速度（PWV ），血压，血脂，空腹血糖（FBG ），高敏C反应蛋白（hs-CRP），空腹胰岛素（FINS），胰岛素抵抗指数（HOMA-IR），腰围，体质量指数（BMI）的检测。【结果】DM 患者组颈--股动脉PWV显著高于对照组（ P＜0．05），多因素回归分析显示：PWV与FBG ，hs-CRP ，FINS ，血压，血脂，患者年龄，以及 HOMA-IR表现为正相关。【结论】老年DM会使动脉僵硬度显著增大，且随着MS并发呈上升趋势。
【목적】탐토노년당뇨병（DM ）합병대사종합정（MS）환자동맥강경도적변화급영향인소。【방법】선취래본원요양적246례노년DM환자，이유무합병MS분위MS조（ n＝120）화무MS조（ n＝126），령선취62례건강노년인작위대조조。대소유환자진행맥박파전도속도（PWV ），혈압，혈지，공복혈당（FBG ），고민C반응단백（hs-CRP），공복이도소（FINS），이도소저항지수（HOMA-IR），요위，체질량지수（BMI）적검측。【결과】DM 환자조경--고동맥PWV현저고우대조조（ P＜0．05），다인소회귀분석현시：PWV여FBG ，hs-CRP ，FINS ，혈압，혈지，환자년령，이급 HOMA-IR표현위정상관。【결론】노년DM회사동맥강경도현저증대，차수착MS병발정상승추세。
To explore the changes and influential factors of arterial stiffness in elderly patients with diabetesmellitus (DM) mergedmet abolicsyndrome(MS).[Methods]Totally 246 elderly patients with DM in our sanatorium were chosen .According to the merging or not ,all patients were divided into merging MS group( n=120) and no merging MS group( n=126) .Other 62 healthy old people were chosen as the control group .Pulse wave conduction velocity (PWV) ,blood pressure ,blood lipid ,fasting blood glucose(FBG) ,high-sensitivity C-re-active protein(hs-CRP) ,fasting insulin(FINS) ,insulin resistance index (HOMA IR) ,waist circumference and body mass index(BMI) of all patients were measured .[Results] Neck-femoral artery PWV in DM patients was significantly higher than that in control group(P<0.05).Multiple-factor regression analysis showed that PWV was positively correlated with FBG ,hs-CRP ,FINS ,blood pressure ,blood lipid ,patients'age and HOMA-IR .[Conclusion]Senile DM can significantly increase arterial stiffness .Arterial stiffness has a rising trend due to the merging MS.