CAJ | 학술논문

建立了新型“香料”毒品中Hu-210的液相色谱分析方法。以甲醇作为提取溶剂。采用岛津ODS-SP型（250mm×4.6mm，5μm）色谱柱，紫外检测器以215nm作为检测波长。以（甲醇-乙腈）-高纯水为流动相进行梯度洗脱，流速1mL·min-1，柱温35℃，进样量10μL。在优化条件下，Hu-210在1~100μg·mL-1范围内线性良好，相关系数大于0.9999，检出限（S/N≥3.3）为0.2ng·μL-1。方法快速、灵敏、准确、可靠，适用于新型“香料”毒品样本中Hu-210成分的定量测定。
건립료신형“향료”독품중Hu-210적액상색보분석방법。이갑순작위제취용제。채용도진ODS-SP형（250mm×4.6mm，5μm）색보주，자외검측기이215nm작위검측파장。이（갑순-을정）-고순수위류동상진행제도세탈，류속1mL·min-1，주온35℃，진양량10μL。재우화조건하，Hu-210재1~100μg·mL-1범위내선성량호，상관계수대우0.9999，검출한（S/N≥3.3）위0.2ng·μL-1。방법쾌속、령민、준학、가고，괄용우신형“향료”독품양본중Hu-210성분적정량측정。
A high performance liquid chromatographic method was established for determination of Hu-210 in novel “spice”drugs. Methanol was used as the solvent to extract. The separation was performed on a Shimadzu ODS-SP column(250mm × 4.6mm, 5μm), using(methanol- acetonitrile)water as mobile phase. The percentage of organic phase changed between 80% and 95% in 15min with a linear gradient elution. Flow rate was set at 1mL·min-1, column temperature was 35℃and injection volume was 10μL. The detection wavelength of UV detec-tor was set as 215nm. Good linearity was achieved over the range of 1~100μg·mL-1, with correlation coefficients>0.9999. Limit of detection (S/N≥3.3)was 0.2ng·μL-1. Results showed that the method was rapid, sensitive and accurate, and was applicable to quantitative determination of Hu-210 in Novel“Spice”Drugs.