CAJ | 학술논문

目的观察疱疹性咽峡炎患儿的早期临床症状和体征,以便早期识别有可能发展为手足口病的疱疹性咽峡炎患儿.方法选取我院2012-2013年儿科病区临床早期诊断为疱疹性咽峡炎患儿80例,随病情进展分为3组.A组为单纯疱疹性咽峡炎组患儿42例；B组为疱疹性咽峡炎发展为手足口病组患儿28例,C组为发展为重症手足口病患儿10例.分别检测3组患儿血常规及淋巴细胞计数、中性粒细胞计数,并监测其发热程度、血压、心率、呼吸及消化系统、神经系统症状.结果 A、B、C组患儿白细胞计数、淋巴细胞计数、中性粒细胞计数比较差异均无统计学意义(P均＞0.05)；患儿发热程度、热程、心率、呼吸频率、收缩压、舒张压比较差异均有统计学意义(F值分别为5.03、3.62、4.83、3.65、6.72、3.74,P均＜0.05)；同时伴有明显食欲减退、呕吐、腹泻消化道症状和易惊、肢体抖动、嗜睡神经系统症状,差异均有统计学意义(x2值分别为6.10、5.75、4.86、3.58、3.42、4.35,P均＜0.05).结论疱疹性咽峡炎患儿如热度高、热程长,心率、呼吸偏快、血压偏高,伴有食欲减退、呕吐或腹泻和/或伴有易惊或肢体抖动、嗜睡症状,进一步发展为手足口病的可能性大.
목적 관찰포진성인협염환인적조기림상증상화체정,이편조기식별유가능발전위수족구병적포진성인협염환인.방법 선취아원2012-2013년인과병구림상조기진단위포진성인협염환인80례,수병정진전분위3조.A조위단순포진성인협염조환인42례；B조위포진성인협염발전위수족구병조환인28례,C조위발전위중증수족구병환인10례.분별검측3조환인혈상규급림파세포계수、중성립세포계수,병감측기발열정도、혈압、심솔、호흡급소화계통、신경계통증상.결과 A、B、C조환인백세포계수、림파세포계수、중성립세포계수비교차이균무통계학의의(P균＞0.05)；환인발열정도、열정、심솔、호흡빈솔、수축압、서장압비교차이균유통계학의의(F치분별위5.03、3.62、4.83、3.65、6.72、3.74,P균＜0.05)；동시반유명현식욕감퇴、구토、복사소화도증상화역량、지체두동、기수신경계통증상,차이균유통계학의의(x2치분별위6.10、5.75、4.86、3.58、3.42、4.35,P균＜0.05).결론 포진성인협염환인여열도고、열정장,심솔、호흡편쾌、혈압편고,반유식욕감퇴、구토혹복사화/혹반유역량혹지체두동、기수증상,진일보발전위수족구병적가능성대.
Objective To analyze the relationships and differences of the clin(HFMD) ical signs and the possibility of children with herpangina developing into HFMD by observing the clinical signs.Methods Eighty children diagnosed herpangina clinically firstly were divided into Group A,B and C.Group A included 42 cases with only herpangina,and Group B including 28 cases who were herpangina developing into mild HFMD and Group C including 10 cases with serve HFMD.The clinical signs of the three groups,including blood routine test and lymphocyte count,neutrophil count,and monitor the degree of fever,blood pressure,heart rate,respiratory and digestive system,nervous system symptoms were recorded.Results In Group A,B and C,white blood cell number,lymphocyte number,neutrophil number were no significant difference(P ＞ 0.05).However,fever degree,thermal history,heart rate,respiratory rate,systolic pressure,diastolic pressure were significant differences (F =5.03,3.62,4.83,3.65,6.72,3.74 ; P ＜ 0.05).Meanwhile The sigh of loss of appetite,vomiting,diarrhea,gastrointestinal symptoms and easily frightened,limb jitter,sleepiness were statistically significant(x2 =6.10,5.75,4.86,3.58,3.42,4.35;P ＜0.05).Conclusion The herpangina children with symptoms and signs such as higher fever and higher blood pressure,simultaneously with diarrhea,vomiting,hyperarousal and amyostasia,have the more chance to develop HFMD.