疑难病杂志
疑難病雜誌
의난병잡지
JOURNAL OF DIFFICULT AND COMPLICATED CASES
2014年
8期
814-815,819
,共3页
徐辉%郑坚江%多力坤%多鲁坤
徐輝%鄭堅江%多力坤%多魯坤
서휘%정견강%다력곤%다로곤
降钙素原%内毒素%诊断价值%腹部创伤术后%肺部细菌感染
降鈣素原%內毒素%診斷價值%腹部創傷術後%肺部細菌感染
강개소원%내독소%진단개치%복부창상술후%폐부세균감염
Procalcitonin%Endotoxin%Diagnosis value%Post-operation of abdominal trauma%Pulmonary bacterial in-fection
目的：研究降钙素原（PCT）与内毒素（ET）在腹部创伤术后患者肺部感染中的诊断价值。方法选择2005年1月-2012年5月腹部创伤术后肺部感染的患者140例，并根据肺部感染的病原体种类分为细菌组（44例）与非细菌组（96例），检测2组患者的血清PCT与ET水平。 PCT＜0热．5 ng/ml为阴性，≥0．5 ng/ml为阳性；ET＜0．035 EU/ml为阴性，≥0．035 EU/ml为阳性。计算两者的诊断敏感度与特异度。结果细菌组 PCT 阳性率为90．91％（40/44），非细菌组阳性率为5．21％（5/96）。细菌组 ET 阳性率为68．18％（30/44），非细菌组阳性率为34．38％（33/96）。根据计算可知，PCT检测敏感度为90．91％（40/44），特异度为94．79％（91/96）；ET检测敏感度为68．18％（30/44），特异度为65．62％（63/96）。2组比较差异均具有统计学意义（ P ＜0．05）。结论降钙素原、内毒素检测对诊断腹部创伤术后患者肺部感染具有临床意义。
目的：研究降鈣素原（PCT）與內毒素（ET）在腹部創傷術後患者肺部感染中的診斷價值。方法選擇2005年1月-2012年5月腹部創傷術後肺部感染的患者140例，併根據肺部感染的病原體種類分為細菌組（44例）與非細菌組（96例），檢測2組患者的血清PCT與ET水平。 PCT＜0熱．5 ng/ml為陰性，≥0．5 ng/ml為暘性；ET＜0．035 EU/ml為陰性，≥0．035 EU/ml為暘性。計算兩者的診斷敏感度與特異度。結果細菌組 PCT 暘性率為90．91％（40/44），非細菌組暘性率為5．21％（5/96）。細菌組 ET 暘性率為68．18％（30/44），非細菌組暘性率為34．38％（33/96）。根據計算可知，PCT檢測敏感度為90．91％（40/44），特異度為94．79％（91/96）；ET檢測敏感度為68．18％（30/44），特異度為65．62％（63/96）。2組比較差異均具有統計學意義（ P ＜0．05）。結論降鈣素原、內毒素檢測對診斷腹部創傷術後患者肺部感染具有臨床意義。
목적：연구강개소원（PCT）여내독소（ET）재복부창상술후환자폐부감염중적진단개치。방법선택2005년1월-2012년5월복부창상술후폐부감염적환자140례，병근거폐부감염적병원체충류분위세균조（44례）여비세균조（96례），검측2조환자적혈청PCT여ET수평。 PCT＜0열．5 ng/ml위음성，≥0．5 ng/ml위양성；ET＜0．035 EU/ml위음성，≥0．035 EU/ml위양성。계산량자적진단민감도여특이도。결과세균조 PCT 양성솔위90．91％（40/44），비세균조양성솔위5．21％（5/96）。세균조 ET 양성솔위68．18％（30/44），비세균조양성솔위34．38％（33/96）。근거계산가지，PCT검측민감도위90．91％（40/44），특이도위94．79％（91/96）；ET검측민감도위68．18％（30/44），특이도위65．62％（63/96）。2조비교차이균구유통계학의의（ P ＜0．05）。결론강개소원、내독소검측대진단복부창상술후환자폐부감염구유림상의의。
Objective To investigate the effect of procalcitonin ( PCT) and endotoxin ( ET) in abdominal trauma pa-tients with pulmonary infection .Methods From 2005 January to 2012 May, 140 patients of pulmonary infection after abdomi-nal injury operation were enrolled , and according to the pathogenic species of pulmonary infection , they were divided into bac-terial infection group (44 cases) and non-bacterial infection group (96 cases), serum PCT and ET levels were detected in the 2 groups of patient .PCT<0.5 ng/ml was defined as negative ,PCT≥0.5 ng/ml was defined as positive;ET<0.035 EU/ml was defined as negative , ET≥0.035 EU/ml was defined as positive .Calculated the sensitivity and specificity of the two groups.Results Bacterial group's PCT positive rate of was 90.91%(40/44), non-bacterial group's positive rate was 5.21%(5/96).Bacteria group's ET positive rate was 68.18%(30/44), non-bacterial group's positive rate was 34.38%(33/96). According to the calculation, the PCT detection sensitivity was 90.91%(40/44), the specificity was 94.79%(91/96);ET detection sensitivity was 68.18%(30/44), the specificity was 65.62%(63/96).The differences between the 2 groups were statistically significant ( P <0.05).Conclusion It demonstrated that the detection of procalcitonin and endotoxin has clini-cal significance in the diagnosis of pulmonary infection in patients after abdominal trauma .
