新医学
新醫學
신의학
NEW CHINESE MEDICINE
2014年
8期
515-518
,共4页
糖尿病,2型%糖尿病周围神经病变%相关因素
糖尿病,2型%糖尿病週圍神經病變%相關因素
당뇨병,2형%당뇨병주위신경병변%상관인소
Diabetesmellitus,type2%Diabeticperipheralneuropathy%Relevantfactors
目的：探讨住院2型糖尿病患者糖尿病周围神经病变（DPN）的相关因素。方法收集219例2型糖尿病住院患者的临床资料，根据是否合并DPN，分为DPN组（153例）及非DPN组（66例），比较两组患者的临床资料，采用Logistic回归分析探讨住院2型糖尿病患者DPN 的相关因素。结果与非DPN组相比，DPN组年龄高、糖尿病病程长（P＜0.01），糖化血红蛋白（HbA1 c ）、空腹血糖、餐后2 h血糖、尿微量白蛋白排泄率（UAER）水平及合并糖尿病视网膜病变（DR）比例高（P＜0.05或0.01）。Logistic回归分析显示DPN与年龄、HbA1 c、UAER及合并DR有关（OR值分别为1.071、1.315、1.039、2.255）。结论年龄、HbA1 c、UAER及合并DR是住院2型糖尿病患者DPN的重要相关因素，高龄、HbA1 c高、UAER高及合并 DR的住院2型糖尿病患者可能更易发生DPN。
目的：探討住院2型糖尿病患者糖尿病週圍神經病變（DPN）的相關因素。方法收集219例2型糖尿病住院患者的臨床資料，根據是否閤併DPN，分為DPN組（153例）及非DPN組（66例），比較兩組患者的臨床資料，採用Logistic迴歸分析探討住院2型糖尿病患者DPN 的相關因素。結果與非DPN組相比，DPN組年齡高、糖尿病病程長（P＜0.01），糖化血紅蛋白（HbA1 c ）、空腹血糖、餐後2 h血糖、尿微量白蛋白排洩率（UAER）水平及閤併糖尿病視網膜病變（DR）比例高（P＜0.05或0.01）。Logistic迴歸分析顯示DPN與年齡、HbA1 c、UAER及閤併DR有關（OR值分彆為1.071、1.315、1.039、2.255）。結論年齡、HbA1 c、UAER及閤併DR是住院2型糖尿病患者DPN的重要相關因素，高齡、HbA1 c高、UAER高及閤併 DR的住院2型糖尿病患者可能更易髮生DPN。
목적：탐토주원2형당뇨병환자당뇨병주위신경병변（DPN）적상관인소。방법수집219례2형당뇨병주원환자적림상자료，근거시부합병DPN，분위DPN조（153례）급비DPN조（66례），비교량조환자적림상자료，채용Logistic회귀분석탐토주원2형당뇨병환자DPN 적상관인소。결과여비DPN조상비，DPN조년령고、당뇨병병정장（P＜0.01），당화혈홍단백（HbA1 c ）、공복혈당、찬후2 h혈당、뇨미량백단백배설솔（UAER）수평급합병당뇨병시망막병변（DR）비례고（P＜0.05혹0.01）。Logistic회귀분석현시DPN여년령、HbA1 c、UAER급합병DR유관（OR치분별위1.071、1.315、1.039、2.255）。결론년령、HbA1 c、UAER급합병DR시주원2형당뇨병환자DPN적중요상관인소，고령、HbA1 c고、UAER고급합병 DR적주원2형당뇨병환자가능경역발생DPN。
Objective Toexplorerelevantfactorsofdiabeticperipheralneuropathy(DPN)inhospi-talizedpatientswithtype2diabetesmellitus.Methods Atotalof219patientswithtype2diabeteswerere-cruited into this study and divided into the DPN (n=1 53)and non-DPN groups (n=66)according to periph-eral neuropathy. Basic clinical data were statistically compared between two groups. Logistic regression analysis wasadoptedtoidentifyrelevantfactorsofDPN.Results Comparedwiththenon-DPNgroup,patientsinthe DPN group were older and had a longer duration of diabetes (both P<0.01 ). The levels of glycosylated hemo-globin (HbA1 c ),fasting blood glucose (FPG),2 hour postprandial blood glucose (2hPG),urinary albumin excretory rate (UAER)and the incidence of diabetic retinopathy (DR)in DPN patients were significantly higher than those in non-DNP counterparts (P<0.05 or P<0.01 ). Logistic regression analysis revealed that age,HbA1 c ,UAER and complication with DR were significantly correlated with DPN (OR were 1.071 , 1.315,1.039and2.255,respectively).Conclusions Age,HbA1c,UAERandcomplicationwithDRare pivotal relevant factors of DPN in hospitalized patients with type 2 diabetes mellitus. Diabetic patients who are older,have higher levels of HbA1 c and UAER and are complicated with DR have a high incidence of DPN.
