CAJ | 학술논문

原发性三叉神经痛严重影响患者的生命健康，因其发病机制未明，所以目前尚缺乏有效的治疗方法。临床主要的治疗方法有药物治疗、手术治疗、放射治疗、中医治疗、基因治疗和其他疗法等，每种方法各有利弊，其中基因治疗是近年研究的热门方向。该文即对基因方法治疗原发性三叉神经痛的原理、技术及主要内容的实验研究进展作一综述。
원발성삼차신경통엄중영향환자적생명건강，인기발병궤제미명，소이목전상결핍유효적치료방법。림상주요적치료방법유약물치료、수술치료、방사치료、중의치료、기인치료화기타요법등，매충방법각유리폐，기중기인치료시근년연구적열문방향。해문즉대기인방법치료원발성삼차신경통적원리、기술급주요내용적실험연구진전작일종술。
Primarytrigeminalneuralgiaseverelyaffectsthepatients'health.Currently,noeffective therapy for primary trigeminal neuralgia has been determined because the underlying pathogenesis remains elu-sive. Major clinical treatments available for primary trigeminal neuralgia include drug therapy,surgical ap-proach,radiotherapy,traditional Chinese medicine therapy,gene therapy,etc. These options have respective advantages and disadvantages. Gene therapy as a promising approach is becoming a research focus. Here,we reviewed recent progresses regarding the principle,technique and main contents of gene therapy against primary trigeminal neuralgia.