CAJ | 학술논문

目的：研究角膜穿孔( corneal perforation,CP)患者的临床发病特点。 　　方法：回顾性分析1995-07/2010-07福建医科大学附属第一医院住院确诊的CP患者72例72眼,分析其患者临床特点。 　　结果：福建地区角膜溃疡穿孔发病率逐年上升,男女发病率比为17：7,48岁为发病集中年龄,产业工人23例(32%),23例有明确外伤史,菌属鉴定结果：前两位为：真菌感染和棘阿米巴原虫感染。其中10例有糖皮质激素用药史。 　　结论：外伤、真菌性、棘阿米巴角膜炎、蚕食性角膜炎等所致CP的原发病因多种多样,福建地区CP多发于中老年的男性,多数外伤为诱因,致病菌属以真菌感染为主。
목적：연구각막천공( corneal perforation,CP)환자적림상발병특점。 　　방법：회고성분석1995-07/2010-07복건의과대학부속제일의원주원학진적CP환자72례72안,분석기환자림상특점。 　　결과：복건지구각막궤양천공발병솔축년상승,남녀발병솔비위17：7,48세위발병집중년령,산업공인23례(32%),23례유명학외상사,균속감정결과：전량위위：진균감염화극아미파원충감염。기중10례유당피질격소용약사。 　　결론：외상、진균성、극아미파각막염、잠식성각막염등소치CP적원발병인다충다양,복건지구CP다발우중노년적남성,다수외상위유인,치병균속이진균감염위주。
AIM: To study the clinical characteristics of corneal perforation ( CP) . METHODS:A retrospective analysis in July 1995 to July 2010 the First Affiliated Hospital of Fujian Medical University diagnosed CP 72 patients ( 72 eyes ) , clinical characteristics of all the patients were analyzed. RESULTS: The incidence of corneal ulcer perforation rised year by year, the morbidity of male and female was 17:7, the onset age focused on 48 years old. Of 23 industrial workers ( 32%) with clear history of trauma, pathogeny identification results:top two:fungal infection and Acanthamoeba keratitis. A using history of glucocorticoid was found in 10 cases. CONCLUSION:There are plenty of primary causes of CP such as traumas, fungal infection, Acanthamoeba keratitis, eroded keratitis, etc. CP happens in middle-aged males in Fujian province, most traumas are the causes, the main pathogenic bacteria is fungal infection.