CAJ | 학술논문

目的：本研究分析了莪术、鱼腥草、土茯苓三种中药对解脲支原体（Uu）临床分离株的体外抑菌作用，并确定了它们的最小抑菌浓度（MIC）。方法采集临床标本，在体外培养获得Uu临床分离菌株，将三种中药各制成药液，用微量稀释法测定各中药对Uu临床分离菌株的最小抑菌浓度。结果鱼腥草MIC为3.90mg/mL，莪术MIC为3.90mg/mL，土茯苓MIC为7.81mg/mL。结论三种中药对Uu临床分离菌株均显示较好的体外抑制作用，效果以鱼腥草最佳，莪术次之，土茯苓最后。
목적：본연구분석료아술、어성초、토복령삼충중약대해뇨지원체（Uu）림상분리주적체외억균작용，병학정료타문적최소억균농도（MIC）。방법채집림상표본，재체외배양획득Uu림상분리균주，장삼충중약각제성약액，용미량희석법측정각중약대Uu림상분리균주적최소억균농도。결과어성초MIC위3.90mg/mL，아술MIC위3.90mg/mL，토복령MIC위7.81mg/mL。결론삼충중약대Uu림상분리균주균현시교호적체외억제작용，효과이어성초최가，아술차지，토복령최후。
Objective To analyze the in vitro antibacterial effect of three types of traditional Chinese medicine (TCM) of curcuma zedoary,houttuynia cordata and rhizoma smilacis glabrae on clinical isolates of ureaplasma urealyticum (Uu),and to confirm their minimum inhibitory concentration (MIC). Methods Clinical samples were collected and cultured in vitro to obtain clinical isolates of Uu.Three types of TCM were made into solutions,and the MIC of each TCM against clinical isolates were measured via microdilution method. Results The MIC of houttuynia cordata was 3.90 mg/mL,the MIC of curcuma zedoary was 3.90 mg/mL and the MIC of rhizoma smilacis glabrae was 7.81 mg/mL. Conclusion The three types of TCM shows a favorable in vitro inhibitory effect against clinical isolates of Uu.The houttuynia cordata has the best effect,the curcuma zedoary the second and the rhizoma smilacis glabrae,the worst.