CAJ | 학술논문

目的：探讨不同右室起搏比率对长R-R间期房颤合并心衰患者血浆脑钠肽的临床效果。方法选取2010年1月～2011年12月在我院进行治疗46例的R-R间期房颤的患者，左室功能正常者分对照组，左室功能不正常者为治疗组，比较患者治疗前后右室起搏比率、LAD、LVEF以及血浆NT-proBNP。结果治疗组患者治疗1年之后LAD值为（35.10±1.78）mm，明显高于对照组的（39.24±2.14）mm，两组相比具有显著性差异（P＜0.05）；治疗组患者的LVEF为（57.3±3.6）%，明显低于对照组的（64.1±4.8）%，两组相比具有显著性差异（P＜0.05）；治疗组患者的血浆NT-proBNP值为（345.1±11.6）pg/mL，明显高于对照组的（78.2±9.8）pg/mL，两组相比具有显著性差异（P＜0.05）。结论对长R-R间期房颤合并心衰患者进行不同的右室起搏比率，治疗后，取得了较好的临床效果，LAD明显增大，LVEF明显降低，而血浆NT-proBNP明显升高，值得在临床上推广使用。
목적：탐토불동우실기박비솔대장R-R간기방전합병심쇠환자혈장뇌납태적림상효과。방법선취2010년1월～2011년12월재아원진행치료46례적R-R간기방전적환자，좌실공능정상자분대조조，좌실공능불정상자위치료조，비교환자치료전후우실기박비솔、LAD、LVEF이급혈장NT-proBNP。결과치료조환자치료1년지후LAD치위（35.10±1.78）mm，명현고우대조조적（39.24±2.14）mm，량조상비구유현저성차이（P＜0.05）；치료조환자적LVEF위（57.3±3.6）%，명현저우대조조적（64.1±4.8）%，량조상비구유현저성차이（P＜0.05）；치료조환자적혈장NT-proBNP치위（345.1±11.6）pg/mL，명현고우대조조적（78.2±9.8）pg/mL，량조상비구유현저성차이（P＜0.05）。결론대장R-R간기방전합병심쇠환자진행불동적우실기박비솔，치료후，취득료교호적림상효과，LAD명현증대，LVEF명현강저，이혈장NT-proBNP명현승고，치득재림상상추엄사용。
Objective To explore the clinical effects of different right ventricular pacing percentages on plasma brain natriuretic peptide in patients with atrial fibrillation in long R-R interval complicated with heart failure. Methods 46 patients with atrial fibrillation in R-R interval who were treated in our hospital from January 2010 to December 2011 were selected.Those with normal left ventricular function were assigned to a control group,while those with abnormal left ventricular function were assigned to a treatment group. Right ventricular pacing percentages,LAD,LVEF and plasma NT-proBNP in patients before and after the treatment were compared. Results After 1 year of the treatment,LAD value in the treatment group was(35.10±1.78)mm, significantly higher than that of (39.24±2.14)mm in the control group,and the difference was statistically significant(P < 0.05);LVEF in the treatment group was(57.3±3.6)%,significantly lower than that of (64.1±4.8)% in the control group,and the difference was statistically significant(P<0.05);plasma NT-proBNP value in the treatment group was (345.1±11.6) pg/mL,significantly higher than that of(78.2±9.8)pg/mL in the control group,and the difference was statistically significant(P<0.05). Conclusion Different right ventricular pacing percentages for patients with atrial fibrillation in long R-R interval complicated with heart failure have a favorable clinical effect,showing that LAD significantly increased, LVEF significantly lowered, and plasma NT-proBNP significantly increased.The treatment is therefore worthy of clinical promotion and application.