CAJ | 학술논문

目的：对硫酸镁在妊娠期高血压疾病的治疗中不同给药方式的应用效果进行观察，为今后临床工作更好地应用硫酸镁治疗妊娠期高血压疾病取得更好的疗效提供依据。方法选取我院2008年1月～2013年12月期间进行妊娠期高血压疾病治疗的患者110例，对其进行回顾性分析，随机分为肌肉注射组（A组）和静脉滴注组（B组），其中A组50例，B组60例。观察所有患者的临床表现（蛋白尿、水肿、头痛）、血压变化以及并发症的发生情况。同时对患者的妊娠结局进行观察，并且追踪观察新生儿的Apgar评分。结果对两组患者的治疗效果进行分析，在临床表现（蛋白尿、水肿、头痛）、妊娠结局和新生儿的Apgar评分方面无统计学差异（P＞0.05），在血压变化和并发症发生等方面差异有统计学意义（P＜0.05）。结论在妊娠期高血压疾病的治疗中，硫酸镁肌注和静滴均可以明显改善妊娠期高血压疾病患者的症状，有效地降低血压，降低妊娠期高血压疾病引起的并发症的发生率，保证母婴的安全，但静脉途径明显优于肌肉注射，值得临床推广应用。
목적：대류산미재임신기고혈압질병적치료중불동급약방식적응용효과진행관찰，위금후림상공작경호지응용류산미치료임신기고혈압질병취득경호적료효제공의거。방법선취아원2008년1월～2013년12월기간진행임신기고혈압질병치료적환자110례，대기진행회고성분석，수궤분위기육주사조（A조）화정맥적주조（B조），기중A조50례，B조60례。관찰소유환자적림상표현（단백뇨、수종、두통）、혈압변화이급병발증적발생정황。동시대환자적임신결국진행관찰，병차추종관찰신생인적Apgar평분。결과대량조환자적치료효과진행분석，재림상표현（단백뇨、수종、두통）、임신결국화신생인적Apgar평분방면무통계학차이（P＞0.05），재혈압변화화병발증발생등방면차이유통계학의의（P＜0.05）。결론재임신기고혈압질병적치료중，류산미기주화정적균가이명현개선임신기고혈압질병환자적증상，유효지강저혈압，강저임신기고혈압질병인기적병발증적발생솔，보증모영적안전，단정맥도경명현우우기육주사，치득림상추엄응용。
Objective To observe and contrast the application effect of the different methods of administration,how to use magnesium sulfate in the treating of hypertensive disorder complicating pregnancy, provide the basis evidence for better effect of using magnesium sulfate in the treating of hypertensive disorder complicating pregnancy from now on. Methods To select the patients with hypertensive disorder complicating pregnancy from our hospital from January 2008 to December 2013,for the retrospective analysis, randomming for two groups,intramuscular injection(group A) and intravenous drip (group B),inside 50 cases in group A and 60 cases in group B.Observe the clinical manifestation (proteinuria、hydroncus、headache)、the changing of blood pressure and the occurrence of complication.At the same time observe the final result of pregnancy,in addition,follow the trail of giving a mark of Apgar with the neonatus. Results Analyse the treatment effect of the patients,at the clinical manifestation(proteinuria、hydroncus、headache)、the final result of pregnancy and the mark of Apgar with the neonatus,There is no statistical difference(P > 0.05). At the changing of blood pressure and the occurrence of complication, there is statistical difference(P < 0.05). Conclusion At treating of hypertensive disorder complicating pregnancy,intramuscular injection and intravenous drip can improve the symptom,lower blood pressure effectively,lower the incidence rate of complication with hypertensive disorder complicating pregnancy,ensure the safe of mother and baby,but the intravenous drip is better than intramuscular injection,it is worth to spread the application in clinic.