中国医药科学
中國醫藥科學
중국의약과학
CHINA MEDICINE AND PHARMACY
2014年
12期
70-72
,共3页
赵艳海%孙彦秋%陈昱明%刘惠珠%张纯%吴伟艺%陈文尖
趙豔海%孫彥鞦%陳昱明%劉惠珠%張純%吳偉藝%陳文尖
조염해%손언추%진욱명%류혜주%장순%오위예%진문첨
宫颈癌%顺铂%化疗%放疗
宮頸癌%順鉑%化療%放療
궁경암%순박%화료%방료
Cervical cancer%Cisplatin%Chemotherapy%Radiotherapy
目的:评价顺铂同步放化疗方案治疗中晚期宫颈癌的临床疗效。方法选择我院收治的中晚期宫颈癌患者78例,按治疗方式分成对照组和观察组,各39例。对照组单独通过放疗治疗,观察组则通过顺铂同步放化疗进行治疗。放化疗期间每周复查宫颈癌患者的白细胞变化,记录症状,每2周复查肝、肾功能。随访半年后观察肿瘤复发及转移的发生情况。结果观察组总有效率为92.3%,高于对照组总有效率76.9%,差异有统计学意义(P<0.01)。观察组在局部复发以及转移率方面少于对照组,差异有统计学意义(P<0.01)。结论顺铂同步放化疗方案治疗中晚期宫颈癌的疗效确切,并能够降低复发与转移率,临床意义显著。
目的:評價順鉑同步放化療方案治療中晚期宮頸癌的臨床療效。方法選擇我院收治的中晚期宮頸癌患者78例,按治療方式分成對照組和觀察組,各39例。對照組單獨通過放療治療,觀察組則通過順鉑同步放化療進行治療。放化療期間每週複查宮頸癌患者的白細胞變化,記錄癥狀,每2週複查肝、腎功能。隨訪半年後觀察腫瘤複髮及轉移的髮生情況。結果觀察組總有效率為92.3%,高于對照組總有效率76.9%,差異有統計學意義(P<0.01)。觀察組在跼部複髮以及轉移率方麵少于對照組,差異有統計學意義(P<0.01)。結論順鉑同步放化療方案治療中晚期宮頸癌的療效確切,併能夠降低複髮與轉移率,臨床意義顯著。
목적:평개순박동보방화료방안치료중만기궁경암적림상료효。방법선택아원수치적중만기궁경암환자78례,안치료방식분성대조조화관찰조,각39례。대조조단독통과방료치료,관찰조칙통과순박동보방화료진행치료。방화료기간매주복사궁경암환자적백세포변화,기록증상,매2주복사간、신공능。수방반년후관찰종류복발급전이적발생정황。결과관찰조총유효솔위92.3%,고우대조조총유효솔76.9%,차이유통계학의의(P<0.01)。관찰조재국부복발이급전이솔방면소우대조조,차이유통계학의의(P<0.01)。결론순박동보방화료방안치료중만기궁경암적료효학절,병능구강저복발여전이솔,림상의의현저。
Objective To evaluate the clinical effect of cisplatin combined with radiotherapy and chemotherapy in the treatment of middle and advanced stage of cervical cancer. Methods 78 patients with middle and advanced stage of cervical cancer who were admitted to our hospital were allocated to a control group and an observation group according to different treatment methods,with 39 patients in each group. The control group received radiotherapy alone, and the observation group received cisplatin combined with radiotherapy and chemotherapy.Changes of white blood cells of patients with cervical cancer were re-examined weekly during radiotherapy and chemotherapy, and related symptoms were recorded. Hepatic and renal functions were re-examined every two weeks. Relapses and metastasis of tumor in half a year after the follow-up were observed. Results The total effective rate in the observation group was 92.3%,significantly higher than that of 76.9% in the control group,and the difference was statistically significant(P < 0.01).Local relapse rate and metastasis rate in the observation group were lower than those in the control group,and the differences were statistically significant (P < 0.01). Conclusion Cisplatin combined with radiotherapy and chemotherapy in the treatment of middle and advanced stage of cervical cancer has an exact curative effect and helps lower relapse rate and metastasis rate,which is of great clinical significance.