医学理论与实践
醫學理論與實踐
의학이론여실천
The Journal of Medical Theory and Practice
2014年
15期
1968-1969,1972
,共3页
王中华%刘素群%杜莉红
王中華%劉素群%杜莉紅
왕중화%류소군%두리홍
坦索罗辛%索利那新%前列腺增生%膀胱过度活动症
坦索囉辛%索利那新%前列腺增生%膀胱過度活動癥
탄색라신%색리나신%전렬선증생%방광과도활동증
Tamsulosin%Solifenacin%Prostatic hyperplasia%Overactive bladder
目的：探讨大剂量坦索罗辛治疗良性前列腺增生伴膀胱过度活动症的临床疗效。方法：选取本院2011年10月-2013年10月诊治的良性前列腺增生伴膀胱过度活动症患者92例，根据治疗方案分为两组，对照组46例患者采用索利那新治疗，观察组46例患者采用坦索罗辛治疗，疗程12周，给予患者国际前列腺症状评分和膀胱过度活动症评分，比较两组患者的膀胱痉挛、排尿及不良反应情况。结果：观察组患者国际前列腺症状评分、膀胱过度活动症评分均明显低于对照组，观察组患者膀胱痉挛时间、膀胱痉挛次数、尿急次数、尿频次数、夜尿次数均明显小于对照组，差异均有统计学意义（P＜0．05）。观察组患者不良反应发生率低于对照组，差异均无统计意义（P＞0．05）。结论：大剂量坦索罗辛可显著改善良性前列腺增生伴膀胱过度活动症患者临床病症，不良反应少且安全性高，值得推广使用。
目的：探討大劑量坦索囉辛治療良性前列腺增生伴膀胱過度活動癥的臨床療效。方法：選取本院2011年10月-2013年10月診治的良性前列腺增生伴膀胱過度活動癥患者92例，根據治療方案分為兩組，對照組46例患者採用索利那新治療，觀察組46例患者採用坦索囉辛治療，療程12週，給予患者國際前列腺癥狀評分和膀胱過度活動癥評分，比較兩組患者的膀胱痙攣、排尿及不良反應情況。結果：觀察組患者國際前列腺癥狀評分、膀胱過度活動癥評分均明顯低于對照組，觀察組患者膀胱痙攣時間、膀胱痙攣次數、尿急次數、尿頻次數、夜尿次數均明顯小于對照組，差異均有統計學意義（P＜0．05）。觀察組患者不良反應髮生率低于對照組，差異均無統計意義（P＞0．05）。結論：大劑量坦索囉辛可顯著改善良性前列腺增生伴膀胱過度活動癥患者臨床病癥，不良反應少且安全性高，值得推廣使用。
목적：탐토대제량탄색라신치료량성전렬선증생반방광과도활동증적림상료효。방법：선취본원2011년10월-2013년10월진치적량성전렬선증생반방광과도활동증환자92례，근거치료방안분위량조，대조조46례환자채용색리나신치료，관찰조46례환자채용탄색라신치료，료정12주，급여환자국제전렬선증상평분화방광과도활동증평분，비교량조환자적방광경련、배뇨급불량반응정황。결과：관찰조환자국제전렬선증상평분、방광과도활동증평분균명현저우대조조，관찰조환자방광경련시간、방광경련차수、뇨급차수、뇨빈차수、야뇨차수균명현소우대조조，차이균유통계학의의（P＜0．05）。관찰조환자불량반응발생솔저우대조조，차이균무통계의의（P＞0．05）。결론：대제량탄색라신가현저개선량성전렬선증생반방광과도활동증환자림상병증，불량반응소차안전성고，치득추엄사용。
Objective :To investigate clinical effect of high dose tamsulosin in treatment for benign prostatic hyperplasia and overactive bladder .Methods:92 patients with benign prostatic hyperplasia and overactive bladder were selected in hospital from June 2011 to June 2013 .According to treatment ,patients were divided into two groups .46 patients trea-ted solifenacin as control group .46 patients treated tamsulosin as observation group .Course of treatment was 12 weeks .Patients received international prostate symptom score and overactive bladder score .Bladder spasm ;urination;adverse reaction were compared between two groups .Results:International prostate symptom score and overactive blad-der score in observation group were significantly lower than control group .Bladder spasm time ;bladder spasm num-ber;urgency number ;frequent urination number ;nocturia number in observation group were significantly less than control group .Difference was statistically significant (P<0 .05) .Incidence of adverse reaction in observation group was lower than control group .Difference was not statistically significant (P>0 .05) .Conclusion:High dose tamsulosin can significantly improve clinical symptoms of patients with benign prostatic hyperplasia and overactive bladder ,which has less adverse reaction and high safety .That is worthy of clinical use .
