CAJ | 학술논문

目的：探讨甲状腺结节钙化灶的临床意义。方法回顾性分析行手术治疗的430例甲状腺结节患者的彩色超声检查和病理检查资料。结果430例中，甲状腺癌49例（11．4％），其中微钙化灶30例（61．2％）和粗钙化灶3例（6．1％）；良性结节381例（88．6％），其中微钙化灶24例（6．3％）和粗钙化灶39例（10．2％）；两者差异有统计学意义（ P＝0．000）。甲状腺癌与钙化灶相关性分析：钙化类型：微钙化灶55.6％，粗钙化灶7．1％，P＝0．000；年龄：＜45岁48．8％，≥45岁22．6％，P＝0．007；结节数量：单个结节45．0％，多个结节16．7％，P＝0．005；甲状腺癌与性别无关（男性24．2％，女性39．7％，P＝0．130）。结论微钙化灶可以作为彩色超声检查诊断甲状腺癌的特异性指标。
목적：탐토갑상선결절개화조적림상의의。방법회고성분석행수술치료적430례갑상선결절환자적채색초성검사화병리검사자료。결과430례중，갑상선암49례（11．4％），기중미개화조30례（61．2％）화조개화조3례（6．1％）；량성결절381례（88．6％），기중미개화조24례（6．3％）화조개화조39례（10．2％）；량자차이유통계학의의（ P＝0．000）。갑상선암여개화조상관성분석：개화류형：미개화조55.6％，조개화조7．1％，P＝0．000；년령：＜45세48．8％，≥45세22．6％，P＝0．007；결절수량：단개결절45．0％，다개결절16．7％，P＝0．005；갑상선암여성별무관（남성24．2％，녀성39．7％，P＝0．130）。결론미개화조가이작위채색초성검사진단갑상선암적특이성지표。
Objective To explore the relation between thyroid nodular and thyroid calcification .Methods The clinical data of 430 cases with nodular goiter admitted from January 2011 to December 2013 were reviewed.All cases were performed ultrasonography and pathologic examination .Results Of 430 cases,there was thyroid carcinoma in 49 cases(11.4%),including microcalcification in 30 cases(61.2%) and macrocalcification in 3 cases(6.1%);benign lesion in 381 cases(88.6%),including microcalcification in 24 cases(6.3%) and macrocalcification in 39 cases(10.2%).The difference was remarkable (P=0.000).There was remarkable difference in malignant calci-fied nodules ratio between the patients with microcalcification and macrocalcification (55.6%vs 7.1%,P=0.000), between the patients aged 45 years below and above(48.8%vs 22.6%,P=0.007),between the patients with solita-ry and multiple nodules(45.0%vs 16.7%,P=0.005).But there was no statistic difference in malignant calcified nodules ratio between the male and female groups (24.2% vs.39.7%,P=0.130).Conclusion Microcalcification is a highly specific sign to predict thyroid carcinoma in ultrasonography exam .Positive intervention will be performed immediately when calcification appears in thyroid nodules .