中国基层医药
中國基層醫藥
중국기층의약
CHINESE JOURNAL OF PRIMARY MEDICINE AND PHARMACY
2014年
16期
2401-2403
,共3页
鲍曼不动杆菌%重症监护病房%抗药性
鮑曼不動桿菌%重癥鑑護病房%抗藥性
포만불동간균%중증감호병방%항약성
Drug resistance%Intensive care unit%Acinetobacter baumannii
目的：比较ICU与非ICU鲍曼不动杆菌分布和耐药性。方法回顾性对比分析ICU分离出的1079株和非ICU分离出的8413株细菌；细菌鉴定和药敏试验采用VITEK 2 Compact全自动细菌培养鉴定仪。结果 ICU分离鲍曼不动杆菌最多，构成比（29．2％）明显高于非ICU（6．2％）（χ2＝625．955，P＜0．05）；ICU耐亚胺培南鲍曼不动杆菌（IRAB）的检出率（91．7％）明显高于非ICU（43．5％）（χ2＝193．541，P＜0．05）；ICU和非ICU分离细菌的标本均主要来源于痰液，构成比分别为64．0％和32．9％。 ICU和非ICU分离的鲍曼不动杆菌对阿米卡星耐药率较低（20．0％～21．6％），ICU分离的鲍曼不动杆菌对三、四代头孢菌素、酶抑制剂复合药物、碳青霉烯类、喹诺酮类等广谱抗菌药物的耐药率明显高于非 ICU （χ2＝146．124、104．409、253.171、195．646、186．580，均P＜0．05）。结论多重耐药鲍曼不动杆菌在ICU的检出率高，应加强细菌监测，合理用药，降低细菌的耐药性。
目的：比較ICU與非ICU鮑曼不動桿菌分佈和耐藥性。方法迴顧性對比分析ICU分離齣的1079株和非ICU分離齣的8413株細菌；細菌鑒定和藥敏試驗採用VITEK 2 Compact全自動細菌培養鑒定儀。結果 ICU分離鮑曼不動桿菌最多，構成比（29．2％）明顯高于非ICU（6．2％）（χ2＝625．955，P＜0．05）；ICU耐亞胺培南鮑曼不動桿菌（IRAB）的檢齣率（91．7％）明顯高于非ICU（43．5％）（χ2＝193．541，P＜0．05）；ICU和非ICU分離細菌的標本均主要來源于痰液，構成比分彆為64．0％和32．9％。 ICU和非ICU分離的鮑曼不動桿菌對阿米卡星耐藥率較低（20．0％～21．6％），ICU分離的鮑曼不動桿菌對三、四代頭孢菌素、酶抑製劑複閤藥物、碳青黴烯類、喹諾酮類等廣譜抗菌藥物的耐藥率明顯高于非 ICU （χ2＝146．124、104．409、253.171、195．646、186．580，均P＜0．05）。結論多重耐藥鮑曼不動桿菌在ICU的檢齣率高，應加彊細菌鑑測，閤理用藥，降低細菌的耐藥性。
목적：비교ICU여비ICU포만불동간균분포화내약성。방법회고성대비분석ICU분리출적1079주화비ICU분리출적8413주세균；세균감정화약민시험채용VITEK 2 Compact전자동세균배양감정의。결과 ICU분리포만불동간균최다，구성비（29．2％）명현고우비ICU（6．2％）（χ2＝625．955，P＜0．05）；ICU내아알배남포만불동간균（IRAB）적검출솔（91．7％）명현고우비ICU（43．5％）（χ2＝193．541，P＜0．05）；ICU화비ICU분리세균적표본균주요래원우담액，구성비분별위64．0％화32．9％。 ICU화비ICU분리적포만불동간균대아미잡성내약솔교저（20．0％～21．6％），ICU분리적포만불동간균대삼、사대두포균소、매억제제복합약물、탄청매희류、규낙동류등엄보항균약물적내약솔명현고우비 ICU （χ2＝146．124、104．409、253.171、195．646、186．580，균P＜0．05）。결론다중내약포만불동간균재ICU적검출솔고，응가강세균감측，합리용약，강저세균적내약성。
Objective To compare distribution and drug resistance of Acinetobacter baumannii specimen in the intensive care unit(ICU) and the ICU.Methods Retrospective analysis ICU of 1 079 strains isolated and the 8 413 strains of bacteria isolated from ICU , Bacteria identification and drug sensitive test instrument using VITEK 2 Compact automatic bacterial culture identification .Results Most ICU Acinetobacter baumannii separation , form (29.2%) was significantly higher than the ICU (6.2%),the difference was statistically significant (χ2 =625.955, P<0.05).ICU imine resistant Acinetobacter baumannii from south (IRAB)detection rate(91.7%)was significantly higher(43.5%) than the ICU,difference was statistically significant (χ2 =193.541,P<0.05);Specimens of ICU and the ICU isolated bacteria were mainly comes from sputum ,constitute a ratio of 64.0%and 32.9%respectively. ICU and the separation of the ICU Acinetobacter baumannii to amikacin resistant rate was low (20.0%-21.6%),the separation of ICU Acinetobacter baumannii for three or four generation of cephalosporin , composite inhibitor drugs , penicillium carbon alkene ,quinolone antibacterial drugs ,significantly higher percentages of ICU ,difference was statis-tically significant(χ2 =146.124,104.407,253.171,195.646,186.580,all P<0.05).Conclusion Multiple drug resistance of Acinetobacter baumannii in ICU detection rate is high ,the bacteria monitoring should be strengthened , and the rational use of drugs ,reduce the drug resistance of bacteria .
