CAJ | 학술논문

目的：探讨血浆致动脉硬化指数（AIP）及颈内动脉内中膜厚（IMT）与缺血性脑卒中发生的关系。方法选择经头部CT和（或）MRI确诊为缺血性脑卒中患者70例及健康体检者70例，采用多普勒超声检测入组对象 IMT、总胆固醇（TC）、低密度脂蛋白（LDL-C）、甘油三酯（TG）及高密度脂蛋白（HDL-C），计算出 AIP，并进行分析。结果与健康对照组相比，缺血性脑卒中组患者 IMT、TC、TG、LDL-C及 AIP 值明显升高，而 HDL-C下降，差异有统计学意义（P＜0.05）；IMT与AIP呈正相关（r＝0.514，P＝0.001）。结论 AIP与 IMT与缺血性脑卒中的发生密切相关。
목적：탐토혈장치동맥경화지수（AIP）급경내동맥내중막후（IMT）여결혈성뇌졸중발생적관계。방법선택경두부CT화（혹）MRI학진위결혈성뇌졸중환자70례급건강체검자70례，채용다보륵초성검측입조대상 IMT、총담고순（TC）、저밀도지단백（LDL-C）、감유삼지（TG）급고밀도지단백（HDL-C），계산출 AIP，병진행분석。결과여건강대조조상비，결혈성뇌졸중조환자 IMT、TC、TG、LDL-C급 AIP 치명현승고，이 HDL-C하강，차이유통계학의의（P＜0.05）；IMT여AIP정정상관（r＝0.514，P＝0.001）。결론 AIP여 IMT여결혈성뇌졸중적발생밀절상관。
Objective To investigate the relationship between atherogenic index of plasma,carotid intima-media thickness and ischemic stroke.Methods Intima-media thickness(IMT)were examined with color Doppler ultrasound in 70 patients with ischemic stroke confirmed by cranial CT and(or)MRI and 70 subjects for health examination as controls;the level of triglycer-ide(TG),total cholesterol(TC),low-density lipoprotein cholesterol(LDL-C),high density lipo-protein cholesterol(HDL-C) were detected for all subjects and atherogenic index of plasma(AIP)were determined in 70 patients with ischemic stroke and 70 subj ects as controls.Results The levels of IMT,TC,TG,LDL-C and AIP increased significantly in patients with ischemic stroke,and the levels of HDL-C decreased significantly(P<0.05).IMT was correlated with AIP(r=0.514,P=0.001).Con-clusion The development of ischemic stroke is closely correlated with the carotid IMT and AIP.