CAJ | 학술논문

目的：研究牙周炎严重程度对飞行员冠心病患者血清C反应蛋白的影响。方法选取2010年3月～2013年12月期间中国南方航空公司航空卫生管理部做洁牙和牙周治疗的空勤人员中牙周炎患者合并冠心病32例纳入研究对象，根据牙周炎病变程度分为轻度牙周炎组、中度牙周炎组和重度牙周炎组，检测C反应蛋白水平和心功能指标。结果（1）CRP水平为轻度牙周炎组＜中度牙周炎组＜重度牙周炎组，E峰值、E/A比值、LVEF、LVEDD为轻度牙周炎组＞中度牙周炎组＞重度牙周炎组；（2）牙周炎严重程度指标探诊深度、临床附着丧失与CRP水平呈正相关，与E峰值、E/A比值、LVEF、LVEDD呈负相关。结论牙周炎病变程度加重可导致血清C反应蛋白水平增加和心功能恶化，且CRP水平与心功能存在较好的相关性，也提示牙周炎可通过增加炎症反应程度来导致冠心病恶化。
목적：연구아주염엄중정도대비행원관심병환자혈청C반응단백적영향。방법선취2010년3월～2013년12월기간중국남방항공공사항공위생관리부주길아화아주치료적공근인원중아주염환자합병관심병32례납입연구대상，근거아주염병변정도분위경도아주염조、중도아주염조화중도아주염조，검측C반응단백수평화심공능지표。결과（1）CRP수평위경도아주염조＜중도아주염조＜중도아주염조，E봉치、E/A비치、LVEF、LVEDD위경도아주염조＞중도아주염조＞중도아주염조；（2）아주염엄중정도지표탐진심도、림상부착상실여CRP수평정정상관，여E봉치、E/A비치、LVEF、LVEDD정부상관。결론아주염병변정도가중가도치혈청C반응단백수평증가화심공능악화，차CRP수평여심공능존재교호적상관성，야제시아주염가통과증가염증반응정도래도치관심병악화。
Objective To study the effects of periodontitis severity on serum CRP level of pilots with coronary heart disease. Methods pilots patients with coronary heart disease and periodontitis in our hospital from March t2011 o December 2013 were enrolled and divided into mild periodontitis group, moderate periodontitis group and severe periodontitis group. Then C reactive protein level and cardiac function indexes were detected. Results (1) The level of CRP were mild periodontitis grouP<moderate periodontitis grouP<severe periodontitis group;E peak, E/A ratio, LVEF, LVEDD were mild periodontitis group>moderate periodontitis group>severe periodontitis group; (2) Periodontitis severity index probing depth andclinical attachment loss were positively correlated with CRP level, negatively correlated with the E peak, E/A ratio, LVEF, LVEDD.. Conclusion The severity of periodontitis aggravation can increase the serum level of CRP and worsen cardiac function;the level of CRP and cardiac function have a good correlation;it also suggests periodontitis can worsen coronary heart disease by increase the degree of inflammatory reaction.