CAJ | 학술논문

目的：探讨恶性肿瘤患者中抑郁症的发病特点及相关因素。方法采用汉密尔顿抑郁量表（HAMD）及患者一般临床特征调查表对154例恶性肿瘤患者进行数据采集和相关性分析。结果154例不同类型恶性肿瘤的患者中有75例（48.7%）患有抑郁症。其中实体肿瘤患者的抑郁发生率为49.3%（70/142），血液系统恶性肿瘤患者的抑郁发生率为41.7%（5/12）。抑郁发生与恶性肿瘤的病理类型、性别、患者自我健康关注度以及日常锻炼习惯等因素无关，而老龄、晚期、慢性癌痛及一般体力状况较差等相关因素群体的抑郁发生率较高（P＜0.05）。结论恶性肿瘤患者中抑郁发生率较高。对于具有老龄、晚期、伴有慢性癌痛及一般体力较差等因素的患者，需要进行心理和生理方面的干预，以提高患者生活质量和肿瘤治疗依从性。
목적：탐토악성종류환자중억욱증적발병특점급상관인소。방법채용한밀이돈억욱량표（HAMD）급환자일반림상특정조사표대154례악성종류환자진행수거채집화상관성분석。결과154례불동류형악성종류적환자중유75례（48.7%）환유억욱증。기중실체종류환자적억욱발생솔위49.3%（70/142），혈액계통악성종류환자적억욱발생솔위41.7%（5/12）。억욱발생여악성종류적병리류형、성별、환자자아건강관주도이급일상단련습관등인소무관，이노령、만기、만성암통급일반체력상황교차등상관인소군체적억욱발생솔교고（P＜0.05）。결론악성종류환자중억욱발생솔교고。대우구유노령、만기、반유만성암통급일반체력교차등인소적환자，수요진행심리화생리방면적간예，이제고환자생활질량화종류치료의종성。
Objective To determine the characteristics of depression in patient with cancers and further analyze the correlations between depression and cancer. Methods The methods include self-comment and investigation. The Hamilton Depression Scale(HAMD),ECOG(Eastern Cooperative Oncology Group)scores, Verbal rating scale(VRS), the questionnaire of common condition and clinical parameters were collected. All the data were analyzed by single factorχ2 analysis ,multivariate logistic regression methods. Results Among 154 patients with cancer,75 cases (48.7%) were detected as depression. Depression in patients with solid tumors was 49.3%(70/142) ,and that was 41.7%(5/12) of patients with hematological malignancies. No significant differences were observed between depression and the various parameters, such as pathological type, gender, self-health concerns, daily exercise, and so on (P<0.05). It showed that age, clinical stage, chronic pain and general physical condition were correlated with depression (P<0.05). The groups of elderly, advanced cancer, chronic pain and generally poor physical condition had a higher incidence of depression (P<0.05). Conclusion The incidence of depression in patients with malignant tumor is relatively high. In order to improve quality of life and therapeutic compliance, some psychological or physiological aspects of the intervention should be offered to those of elderly, advanced cancer, chronic pain and generally poor physical condition.