CAJ | 학술논문

目的：观察重组组织型纤溶酶原激活剂早期静脉溶栓治疗急性脑梗死的疗效。方法：选取2012年12月-2013年12月笔者所在医院收治的36例急性脑梗死患者，将其随机分成观察组18例与对照组18例，观察组给予重组组织型纤溶酶原激活剂(rt-PA)0.8 mg/kg进行静脉溶栓，给予对照组患者常规的活血化瘀治疗，比较两组治疗前、治疗后1、7、14 d的NIHSS评分。结果：治疗后1、7、14 d观察组的NIHSS评分优于对照组，90 d后治疗总有效率明显高于对照组，差异有统计学意义(P<0.05)。结论：rt-PA静脉溶栓对急性脑梗死的治疗，可以促进神经功能的早期恢复，改善患者90 d的预后，且越早治疗其溶栓的效果越好。
목적：관찰중조조직형섬용매원격활제조기정맥용전치료급성뇌경사적료효。방법：선취2012년12월-2013년12월필자소재의원수치적36례급성뇌경사환자，장기수궤분성관찰조18례여대조조18례，관찰조급여중조조직형섬용매원격활제(rt-PA)0.8 mg/kg진행정맥용전，급여대조조환자상규적활혈화어치료，비교량조치료전、치료후1、7、14 d적NIHSS평분。결과：치료후1、7、14 d관찰조적NIHSS평분우우대조조，90 d후치료총유효솔명현고우대조조，차이유통계학의의(P<0.05)。결론：rt-PA정맥용전대급성뇌경사적치료，가이촉진신경공능적조기회복，개선환자90 d적예후，차월조치료기용전적효과월호。
Objective:To observe the curative effect of early intravenous thrombolysis with rt-PA in the treatment of acute cerebral infarction.Method:36 patients with acute cerebral infarction who were being treated at our hospital from December 2012 to December 2013 were selected,they were randomly divided into the observation group (18 cases) and the control group(18 cases),the observation group were treated through intravenous thrombolytic with rt-PA(0.8 mg/kg), the control group were used activating blood and resolving stasis,the NIHSS score of the two groups before and after treatment of 1,7,14 d was compared. Result:After the treatment of the first,the 7th days,the 14th days,the NIHSS score in the observation group were better than control group,the total efficiency after 90 d was significantly higher than the control group,the difference were statistically significant(P<0.05).Conclusion:Intravenous thrombolysis with r-TPA in the treatment of acute cerebral infarction can promote early recovery of neurological function,improve the prognosis after 90 d,and the earlier treatment begins the better the effect of thrombolysis.