CAJ | 학술논문

目的：：探讨不同宫颈锥切方法治疗宫颈上皮内瘤变Ⅲ级的临床疗效。方法：随机选取宫颈上皮内瘤变Ⅲ级的患者60例,将其随机平均分配为 A、B 两组,其中 A 组患者采用宫颈冷刀锥切术(CKC)进行治疗,B 组患者采用宫颈环形电切术(LEEP)进行治疗,对比两组患者的临床疗效。结果：A 组患者的术中出血量、手术时间明显高于 B 组患者(P<0.05)；A 组患者术后宫颈上皮内瘤复发率、HPV 持续感染率均明显低于 B 组患者(P<0.05)。结论：采用宫颈冷刀锥切术对宫颈上皮内瘤变Ⅲ级患者进行治疗,能够有效的降低患者术后复发率和HPV 感染率,但其手术时间和术中出血情况同宫颈环形电切术相比较差,临床治疗时应根据患者的具体情况选择合适的治疗方案。
목적：：탐토불동궁경추절방법치료궁경상피내류변Ⅲ급적림상료효。방법：수궤선취궁경상피내류변Ⅲ급적환자60례,장기수궤평균분배위 A、B 량조,기중 A 조환자채용궁경냉도추절술(CKC)진행치료,B 조환자채용궁경배형전절술(LEEP)진행치료,대비량조환자적림상료효。결과：A 조환자적술중출혈량、수술시간명현고우 B 조환자(P<0.05)；A 조환자술후궁경상피내류복발솔、HPV 지속감염솔균명현저우 B 조환자(P<0.05)。결론：채용궁경냉도추절술대궁경상피내류변Ⅲ급환자진행치료,능구유효적강저환자술후복발솔화HPV 감염솔,단기수술시간화술중출혈정황동궁경배형전절술상비교차,림상치료시응근거환자적구체정황선택합괄적치료방안。
Objective:To evaluate clinical efficacies of different cervical conization in treatment of cervical intraepithelial neo-plasia grade III. Methods:60 cases with cervical intraepithelial neoplasia grade III were randomly selected and divided into A group and B group, wherein A group was treated with cervical cold knife conization (CKC) treatment, while B group was treated by loop electrosurgical excision procedure (LEEP) treatment. The clinical efficacies of the two groups were compared. Results: The bleeding volume and operation time of A group were significantly greater than those of B group (P<0. 05). The tumor recurrence rate and HPV infection rate of A group were significantly lower than those of B group in the patients with cervical intraepithelial neoplasia (P<0. 05). Conclusions: For the cervical intraepithelial neoplasia patients, the cervical cold knife conization can reduce the recurrence rate and HPV infection rate effectively, but the operation time and intraoperative hemorrhage are relatively poor compared with LEEP. There-fore, the doctor should choose the appropriate therapy according to the specific situation of the patients.