CAJ | 학술논문

目的：对我院呼吸科下呼吸道感染的病原菌分布特点和耐药性进行研究分析。方法回顾我院自2011年1月至2013年1月间收治的961例临床下呼吸道感染住院的患者病例。对患者的痰液标本进行病原菌株的分离，并对其分布和耐药性进行研究。结果961例标本中共分离培养出菌株309株，阳性率为32．2%，其中革兰阴性菌149株(48．2%)，主要为铜绿假单胞菌(58(18．8%))、鲍曼不动杆菌(44(14．2%))和肺炎克雷伯菌(21(6．8%))；革兰阳性菌97株(31．4%)，主要是金黄色葡萄球菌56株(18．1%)，肺炎链球菌23株(7．4%)；真菌63株(20．4%)，主要为白色念珠菌48株(15．5%)。耐药性试验结果表明：亚胺培南和阿米卡星对革兰阴性菌有较好的敏感性，利奈唑胺和万古霉素对革兰阳性菌敏感性好。结论当前呼吸道细菌的耐药性较大，应结合患者耐药检测结果进行合理的用药。
목적：대아원호흡과하호흡도감염적병원균분포특점화내약성진행연구분석。방법회고아원자2011년1월지2013년1월간수치적961례림상하호흡도감염주원적환자병례。대환자적담액표본진행병원균주적분리，병대기분포화내약성진행연구。결과961례표본중공분리배양출균주309주，양성솔위32．2%，기중혁란음성균149주(48．2%)，주요위동록가단포균(58(18．8%))、포만불동간균(44(14．2%))화폐염극뢰백균(21(6．8%))；혁란양성균97주(31．4%)，주요시금황색포도구균56주(18．1%)，폐염련구균23주(7．4%)；진균63주(20．4%)，주요위백색념주균48주(15．5%)。내약성시험결과표명：아알배남화아미잡성대혁란음성균유교호적민감성，리내서알화만고매소대혁란양성균민감성호。결론당전호흡도세균적내약성교대，응결합환자내약검측결과진행합리적용약。
Objective To investigate the pathogenic bacteria distribution and their drug resistance in pa-tients with lower respiratory infection. Methods 961 patients with lower respiratory tract infections were retrospec-tively analyzed. The sputum of all patients was collected and cultured, and then the sputum samples were analyzed. Results 309 strains (32. 2%) were detected out. There were 149 strains of gram-negative bacteria (48. 2%), in-cluding 58 strains of pseudomonas aeruginosa ( 18. 8%) , 44 strains of acinetobacter baumannii ( 14. 2%) , and 21 trains of klebsiella pneumonia (6. 8%). Gram-positive bacteria took up 31. 4%, including 56 strains of staphylococ-cus aureus (18. 1%) and 23 trains of streptococcus pneumonia (7. 4%). Fungi took up 15. 5%. Conclusion Most bacteria in patients with lower respiratory infection show a certain resistance to many antibiotics. Therefore, the rational use of antibiotics is very important for the containment of bacterial resistance.