CAJ | 학술논문

目的：探讨使用短肽肠内营养剂对重症医学科( ICU)危重病患者血糖的影响。方法对60例进行肠内营养支持的ICU危重症患者随机分为两组：两组在积极治疗原发病的基础上,A组30例病人：营养液每日鼻饲持续时间16 h肠内营养泵匀速泵入；B组30例病人：营养液每日间断鼻饲12 h肠内营养泵匀速泵入进行临床随机对照研究,时间为7~27天,绝大多数为10~14天。治疗过程中,监测血糖、生化等指标,找出适合ICU患者的最佳鼻饲持续时间。结果 A组：每日鼻饲持续时间16 h的ICU危重症患者,血糖能较平稳控制；B组：每日间断鼻饲12 h的ICU危重症患者,血糖波动较大。结论通过临床观察,对ICU危重症患者进行肠内营养支持以持续泵入肠内营养液时间在10 h,使用营养液7-14天,血糖波动较小,胃肠道并发症的发生率,生化学指标改善与间断泵入营养液比较对血糖影响较大,胃肠道并发症的发生率、生化学指标改善差异有意义(P<0．05),APACHEⅡ评分与血糖有相关性,持续泵入营养液血糖控制较稳定,两组比较差异有意义,(P<0．05)。经过我们研究说明肠内营养液支持治疗以持续泵入疗效较好,可缩短在ICU的住院时间,预后较好,因病例较少有待进一步研究。
목적：탐토사용단태장내영양제대중증의학과( ICU)위중병환자혈당적영향。방법대60례진행장내영양지지적ICU위중증환자수궤분위량조：량조재적겁치료원발병적기출상,A조30례병인：영양액매일비사지속시간16 h장내영양빙균속빙입；B조30례병인：영양액매일간단비사12 h장내영양빙균속빙입진행림상수궤대조연구,시간위7~27천,절대다수위10~14천。치료과정중,감측혈당、생화등지표,조출괄합ICU환자적최가비사지속시간。결과 A조：매일비사지속시간16 h적ICU위중증환자,혈당능교평은공제；B조：매일간단비사12 h적ICU위중증환자,혈당파동교대。결론통과림상관찰,대ICU위중증환자진행장내영양지지이지속빙입장내영양액시간재10 h,사용영양액7-14천,혈당파동교소,위장도병발증적발생솔,생화학지표개선여간단빙입영양액비교대혈당영향교대,위장도병발증적발생솔、생화학지표개선차이유의의(P<0．05),APACHEⅡ평분여혈당유상관성,지속빙입영양액혈당공제교은정,량조비교차이유의의,(P<0．05)。경과아문연구설명장내영양액지지치료이지속빙입료효교호,가축단재ICU적주원시간,예후교호,인병례교소유대진일보연구。
Objective To investigate the impact of different peptide nasogastric enteral nutrition agent's time on blood glucose for critically ill patients in ICU. Methods 60 patients were randomly divided into two groups. On the basis of the active treatment of primary diseases, the group A (n=30) was given nutrient solution nasogastric en-teral nutrition for 16 hours daily, and the group B was given intermittent nasogastric enteral nutrition for 12 hours dai-ly. The treatment course was 7 to 27 days. The course of treatment, blood glucose monitoring, biochemical indicators were observed to identify the best time for patients in ICU. Results The blood sugar was smoother in the group A than in the group B. Conclusion Through our clinical observations, enteral nutrition support continuous infusion of enteral nutrition for 10 hours, 7-14 days is the best for critically ill patients in ICU, which has smooth blood glucose and low incidence of gastrointestinal complications (P<0. 05).