北方药学
北方藥學
북방약학
JOURNAL OF NORTH PHARMACY
2014年
11期
138-139,140
,共3页
仓怀芹%董加花%申井利%周丽华
倉懷芹%董加花%申井利%週麗華
창부근%동가화%신정리%주려화
鲍氏不动杆菌%抗菌药物%耐药性
鮑氏不動桿菌%抗菌藥物%耐藥性
포씨불동간균%항균약물%내약성
Acinetobacter baumannii Antimicrobial agents%Resistance
目的:探讨分析鲍氏不动杆菌感染分布情况及耐药率。方法:采用纸片扩散(K-B)法对药物进行敏感性实验,对809株鲍氏不动杆菌药物敏感性实验进行回顾分析。结果:鲍氏不动杆菌主要分布在痰液标本中,其次是咽拭子分泌物及脓液中,科室分布主要在ICU,其次为神经外科,鲍氏不动杆菌对头孢曲松、头孢他啶的耐药率较高,分别为53.02%、50%,其次是哌拉西林(40.81%)、头孢吡肟(38%)、美洛培南(34.76%)、亚胺培南(31.25%),左氧氟沙星和头孢哌酮较低,分别为24.25%、20.6%,阿米卡星的耐药率最低,为10.75%。结论:鲍氏不动杆菌对阿米卡星、左氧氟沙星、头孢哌酮较敏感,对其他抗菌药物均有不同程度的耐药性,应根据药敏结果合理选用。
目的:探討分析鮑氏不動桿菌感染分佈情況及耐藥率。方法:採用紙片擴散(K-B)法對藥物進行敏感性實驗,對809株鮑氏不動桿菌藥物敏感性實驗進行迴顧分析。結果:鮑氏不動桿菌主要分佈在痰液標本中,其次是嚥拭子分泌物及膿液中,科室分佈主要在ICU,其次為神經外科,鮑氏不動桿菌對頭孢麯鬆、頭孢他啶的耐藥率較高,分彆為53.02%、50%,其次是哌拉西林(40.81%)、頭孢吡肟(38%)、美洛培南(34.76%)、亞胺培南(31.25%),左氧氟沙星和頭孢哌酮較低,分彆為24.25%、20.6%,阿米卡星的耐藥率最低,為10.75%。結論:鮑氏不動桿菌對阿米卡星、左氧氟沙星、頭孢哌酮較敏感,對其他抗菌藥物均有不同程度的耐藥性,應根據藥敏結果閤理選用。
목적:탐토분석포씨불동간균감염분포정황급내약솔。방법:채용지편확산(K-B)법대약물진행민감성실험,대809주포씨불동간균약물민감성실험진행회고분석。결과:포씨불동간균주요분포재담액표본중,기차시인식자분비물급농액중,과실분포주요재ICU,기차위신경외과,포씨불동간균대두포곡송、두포타정적내약솔교고,분별위53.02%、50%,기차시고랍서림(40.81%)、두포필우(38%)、미락배남(34.76%)、아알배남(31.25%),좌양불사성화두포고동교저,분별위24.25%、20.6%,아미잡성적내약솔최저,위10.75%。결론:포씨불동간균대아미잡성、좌양불사성、두포고동교민감,대기타항균약물균유불동정도적내약성,응근거약민결과합리선용。
Objective:To analyze the drug resistance of 809 clinical strains of Acientobactor banumannii to 10 kindsof antimicrobial agent s for the rational application of antimicrobial agents. Methods:Using disk diffusion method (K2B)for drug susceptibility testing , and drug sensitivity test of 809A. baumanni i to antibiotics was analyzed ret rospectively. Results:The A. baumannii st rains mainly distributed in sputum,followed by the swabs and pus. The main departments was ICU ,followed by the Neurosurgery Department .A banumannii resistant to ceftriaxone,ceftazidine was higher,respectively53.02,50%,followed by piperacillin(40.81%), cefepime(38%), imipenem (34.76%), meropenem (31.25%), levofloxacin and cefoperazone was lower, repectively24.25%、20.6%,the lowest resistance rate of A. baumanni i to the antimicrobial agents was to amikaccin10.75%.Conclusion :Acinetobacter baumannii is sensitive to Amikacin, levofloxacin, cefoperazone, resistance to other antibacterial drugs have different degrees of, should be selected reasonably according to the drug sensitivity results.