北方药学
北方藥學
북방약학
JOURNAL OF NORTH PHARMACY
2014年
11期
5-6
,共2页
七味红花殊胜丸%羟基红花黄色素A%薄层色谱法%高效液相色谱法%质量标准
七味紅花殊勝汍%羥基紅花黃色素A%薄層色譜法%高效液相色譜法%質量標準
칠미홍화수성환%간기홍화황색소A%박층색보법%고효액상색보법%질량표준
Seven kinds of safflower Shusheng pills%Hydroxysafflor yellow A%TLC%HPLC%Quality standards
目的：建立七味红花殊胜丸质量标准。方法：采用薄层色谱法（TLC）对处方中红花进行定性鉴别；用高效液相色谱法（HPLC）测定羟基红花黄色素A含量。结果：TLC定性鉴别分离效果好，斑点显色清晰。羟基红花黄色素A的进样浓度在13.18～79.10μg· ml-1范围内与峰面积积分值呈良好线性关系（r=0.9998）；平均回收率为98.2%，RSD=1.27%（n=6）；每丸含红花以羟基红花黄色素A计应不少于1.0mg。结论：标准可用于该制剂的质量控制。
目的：建立七味紅花殊勝汍質量標準。方法：採用薄層色譜法（TLC）對處方中紅花進行定性鑒彆；用高效液相色譜法（HPLC）測定羥基紅花黃色素A含量。結果：TLC定性鑒彆分離效果好，斑點顯色清晰。羥基紅花黃色素A的進樣濃度在13.18～79.10μg· ml-1範圍內與峰麵積積分值呈良好線性關繫（r=0.9998）；平均迴收率為98.2%，RSD=1.27%（n=6）；每汍含紅花以羥基紅花黃色素A計應不少于1.0mg。結論：標準可用于該製劑的質量控製。
목적：건립칠미홍화수성환질량표준。방법：채용박층색보법（TLC）대처방중홍화진행정성감별；용고효액상색보법（HPLC）측정간기홍화황색소A함량。결과：TLC정성감별분리효과호，반점현색청석。간기홍화황색소A적진양농도재13.18～79.10μg· ml-1범위내여봉면적적분치정량호선성관계（r=0.9998）；평균회수솔위98.2%，RSD=1.27%（n=6）；매환함홍화이간기홍화황색소A계응불소우1.0mg。결론：표준가용우해제제적질량공제。
Objective: To establish the quality standard of seven kinds of safflower Shushen pill. Method: By thin layer chromatography (TLC)was used to identify the prescription Honghua;High performance liquid chromatography (HPLC)determination of hydroxysafflor yellow A content. Results:TLC qualitative identification of good separation effect, spot color clear. Sample concentration of hydroxysafflor yellow A in 13.18~79.10μg·ml-1 scope with the peak area values were good linear relationship (r=0.9998);the average recovery was 98.2%, RSD=1.27%(n=6);each pill contains safflower to hydroxysafflor yellow A meter shall be not less than 1.0mg. Conclusion:The established standard can be used for the quality control of the preparation.
