临床肺科杂志
臨床肺科雜誌
림상폐과잡지
JOUNAL OF CLINICAL PULMONARY MEDICINE
2014年
11期
2009-2011
,共3页
PTB%感染%诊断%PCT%CRP%ESR%WBC
PTB%感染%診斷%PCT%CRP%ESR%WBC
PTB%감염%진단%PCT%CRP%ESR%WBC
pulmonary tuberculosis%infection%diagnosis%PCT%CRP%ESR%WBC
目的：探讨血清降钙素原( PCT)、C-反应蛋白( CRP)、红细胞沉降率( ESR)和白细胞( WBC)计数对肺结核( PTB)合并肺部感染诊断的差异性。方法检测临床确诊为活动性PTB合并肺部感染和未合并感染患者血PCT、CRP、ESR和WBC,采用SPSS 16．0软件对两组资料进行统计分析, MedCalc V12.7.7.0软件进行接受者操作特性( ROC)曲线分析,计算并比较各指标曲线下面积( AUC),确定最佳临界值。结果合并感染组血PCT、CRP、ESR和WBC均高于未合并感染组,差异有统计学意义(均 P<0．01)；4个指标诊断PTB合并肺部感染的AUC分别是0．89、0．75、0．74和0．72,PCT的AUC明显高于其他三个指标,差异有统计学意义(P<0．01)；最佳临界值分别是0．29 ng/ml、15．00 mg/L、37．00 mm/h和7．86×109/L。结论血PCT、CRP、ESR和WBC对诊断PTB合并肺部感染均有一定价值,PCT优于其他3个指标。
目的：探討血清降鈣素原( PCT)、C-反應蛋白( CRP)、紅細胞沉降率( ESR)和白細胞( WBC)計數對肺結覈( PTB)閤併肺部感染診斷的差異性。方法檢測臨床確診為活動性PTB閤併肺部感染和未閤併感染患者血PCT、CRP、ESR和WBC,採用SPSS 16．0軟件對兩組資料進行統計分析, MedCalc V12.7.7.0軟件進行接受者操作特性( ROC)麯線分析,計算併比較各指標麯線下麵積( AUC),確定最佳臨界值。結果閤併感染組血PCT、CRP、ESR和WBC均高于未閤併感染組,差異有統計學意義(均 P<0．01)；4箇指標診斷PTB閤併肺部感染的AUC分彆是0．89、0．75、0．74和0．72,PCT的AUC明顯高于其他三箇指標,差異有統計學意義(P<0．01)；最佳臨界值分彆是0．29 ng/ml、15．00 mg/L、37．00 mm/h和7．86×109/L。結論血PCT、CRP、ESR和WBC對診斷PTB閤併肺部感染均有一定價值,PCT優于其他3箇指標。
목적：탐토혈청강개소원( PCT)、C-반응단백( CRP)、홍세포침강솔( ESR)화백세포( WBC)계수대폐결핵( PTB)합병폐부감염진단적차이성。방법검측림상학진위활동성PTB합병폐부감염화미합병감염환자혈PCT、CRP、ESR화WBC,채용SPSS 16．0연건대량조자료진행통계분석, MedCalc V12.7.7.0연건진행접수자조작특성( ROC)곡선분석,계산병비교각지표곡선하면적( AUC),학정최가림계치。결과합병감염조혈PCT、CRP、ESR화WBC균고우미합병감염조,차이유통계학의의(균 P<0．01)；4개지표진단PTB합병폐부감염적AUC분별시0．89、0．75、0．74화0．72,PCT적AUC명현고우기타삼개지표,차이유통계학의의(P<0．01)；최가림계치분별시0．29 ng/ml、15．00 mg/L、37．00 mm/h화7．86×109/L。결론혈PCT、CRP、ESR화WBC대진단PTB합병폐부감염균유일정개치,PCT우우기타3개지표。
Objective To investigate the differences among serum procalcitonin ( PCT) , C-reactive protein ( CRP) , erythrocyte sedimentation rate ( ESR) and white blood cell count ( WBC) in diagnosing pulmonary tubercu-losis ( PTB) complicated with pulmonary infection. Methods The levels of PCT, CRP, ESR and WBC were detec-ted in active PTB patients complicated with pulmonary infection and patients without infection. The data was analyzed statistically by SPSS16. 0 software. The receiver operating characteristic ( ROC) curves and area under the curve (AUC) of each indicator were analyzed by MedCalc V12. 7. 7. 0 software. AUC and the cut-off values were calculated and compared by ROC. Results Blood PCT, CRP, ESR and WBC level in PTB patients complicated with pulmona-ry infection were all significantly higher those without infection ( P<0. 01 ) . The AUC of four indicators diagnosing PTB complicated with pulmonary infection were 0. 89, 0. 75, 0. 74 and 0. 72 respectively, and AUC of PCT was sig-nificantly higher than the other three indicators (P<0. 01). The cut-off values of PCT, CRP, ESR and WBC were 0. 29 ng/ml, 15. 00 mg/L, 37. 00 mm/h and 7. 86 × 109/L respectively. Conclusion Blood PCT, CRP, ESR and WBC level may be useful in the diagnosis of PTB complicated with pulmonary infection and PCT is better than the other three indicators.
