CAJ | 학술논문

目的：了解兰州市城镇体检人群血脂异常流行病学特点及血脂异常的危险因素，为血脂异常的防治工作提供依据。方法采用分层整群随机抽样抽取兰州市5家医院体检人群共4505例，进行问卷调查、体格检查和实验室检测。结果该人群血脂异常的总患病率为45．79％，以高三酰甘油（TG）为主；血清总胆固醇（TC）、TG、高密度脂蛋白胆固醇（HDL-C）、低密度脂蛋白胆固醇（LDL-C）的总体水平分别为（5．27±1．08）、（1．74±1．38）、（1．41±0．43）、（2．83±0．82）mmol/L ；男性血脂异常率为53．49％，女性为34．93％，男性以35～＜45岁检出率最高，女性以55～＜65岁检出率最高；两性低龄组的 HDL-C均呈现较低水平；心血管危险因素在血脂异常患者中有聚集现象。非条件Logistic回归分析显示，年龄（OR＝1．701）、超重肥胖（OR＝5．560）、腹部肥胖（OR＝2．398）、吸烟（OR＝0．545）、喜食油腻（OR＝5．313）、睡眠质量差（OR＝2．005）、舒张压（OR＝3．061）是血脂异常的危险因素。结论兰州市城镇体检人群血脂异常问题严峻，应采取控制体质量、合理膳食、改善睡眠、控制血压等关键性措施。
목적：료해란주시성진체검인군혈지이상류행병학특점급혈지이상적위험인소，위혈지이상적방치공작제공의거。방법채용분층정군수궤추양추취란주시5가의원체검인군공4505례，진행문권조사、체격검사화실험실검측。결과해인군혈지이상적총환병솔위45．79％，이고삼선감유（TG）위주；혈청총담고순（TC）、TG、고밀도지단백담고순（HDL-C）、저밀도지단백담고순（LDL-C）적총체수평분별위（5．27±1．08）、（1．74±1．38）、（1．41±0．43）、（2．83±0．82）mmol/L ；남성혈지이상솔위53．49％，녀성위34．93％，남성이35～＜45세검출솔최고，녀성이55～＜65세검출솔최고；량성저령조적 HDL-C균정현교저수평；심혈관위험인소재혈지이상환자중유취집현상。비조건Logistic회귀분석현시，년령（OR＝1．701）、초중비반（OR＝5．560）、복부비반（OR＝2．398）、흡연（OR＝0．545）、희식유니（OR＝5．313）、수면질량차（OR＝2．005）、서장압（OR＝3．061）시혈지이상적위험인소。결론란주시성진체검인군혈지이상문제엄준，응채취공제체질량、합리선식、개선수면、공제혈압등관건성조시。
Objective To explore the status and risk factors of the dyslipidemia among health examination population of Lanzhou for providing the intervention measures .Methods According to the stratified cluster random sampling method ,4 505 health exami-nation individuals were recruited for the study from 5 hospitals in the Lanzhou region through questionnaire ,biochemical analysis . Results Prevalence of dyslipidemia of the population was 45 .79% ,high TG was the main type .The level of serum TC ,TG ,HDL-C and LDL-C were (5 .27 ± 1 .08) ,(1 .74 ± 1 .38) ,(1 .41 ± 0 .43) and (2 .83 ± 0 .82)mmol/L .The prevalence was 53 .49% in male , and 34 .93% in female .The prevalence was higher among the group of 35- <45 years old for male and 55- <65 years old for fe-male .The level of HDL-C was low among young people .There was aggregation of risk factors among the participants with dyslipi-demia .Non-conditional logistic regression analysis showed that the risk factors were age (OR=1 .701) ,overweight (OR=5 .560) , abdominal obesity(OR=2 .398) ,smoking(OR=0 .545) ,intake of greasy diet(OR=5 .313) ,sleep quality(OR=2 .005) and diastolic blood pressure(OR=3 .061) .Conclusion Lipid disorders becomes a serious problem in the health examination population ,measures such as rational diet ,weight control ,sleep improvement ,pressure control and quiting smoking must be taken .