CAJ | 학술논문

目的：观察丹红注射液治疗前后行内固定术的股骨干骨折患儿血液流变学的变化及临床意义。方法选择本院收治行内固定术治疗的48例股骨干骨折患儿，根据随机数字表法将其分为两组：对照组患儿术后采用常规治疗，治疗组在上述基础上加用丹红注射液；观察并比较两组患儿的负重时间、骨折愈合时间及治疗前后血液流变学指标。结果治疗组的负重时间和骨折愈合时间均明显短于对照组，差异有统计学意义(P<0.01)；治疗组术后3 d、7 d的血液流变学指标明显低于对照组(P<0.01或P<0.05)。结论丹红注射液可显著改善股骨干骨折内固定术后患儿血液流变学指标，加速骨折愈合。
목적：관찰단홍주사액치료전후행내고정술적고골간골절환인혈액류변학적변화급림상의의。방법선택본원수치행내고정술치료적48례고골간골절환인，근거수궤수자표법장기분위량조：대조조환인술후채용상규치료，치료조재상술기출상가용단홍주사액；관찰병비교량조환인적부중시간、골절유합시간급치료전후혈액류변학지표。결과치료조적부중시간화골절유합시간균명현단우대조조，차이유통계학의의(P<0.01)；치료조술후3 d、7 d적혈액류변학지표명현저우대조조(P<0.01혹P<0.05)。결론단홍주사액가현저개선고골간골절내고정술후환인혈액류변학지표，가속골절유합。
Objective To observe the change and clinical significance of indexes of blood rheology in children with fe-mur shaft fractures after internal fixation operation by using danhong injection. Methods Forty-eight children with fe-mur shaft fractures who were given the operation of internal fixation were randomly devided into two groups. The con-trol group were given the routine therapy, while the study group were given danhong injection besides routine therapy. The weight bearing time, healing time and indexes of blood rheology were compared between two groups. Results The weight bearing and healing time in the study group were lower than that in the control group, there were significant dif-ferences between two groups (P<0.01). Compared with the control group, the indexes of blood rheology 3d, 7d after op-eration in study group were significantly lowered after the therapy (P<0.01 or P<0.05). Conclusion Danhong injection can significantly ameliorate the indexes of blood rheology in children with femur shaft fractures and accelerate fracture healing.